March Madness prop bets: The best odds for 2026 NCAA Tournament winners, 12-5 upsets, more

Selection Sunday is in the rearview mirror — and now, it's time to make your picks. Everybody loves a March Madness Cinderella story, but some years, including 2025, are dominated by the favorites. Last year's tournament was one of just two all-time that featured all four No. 1 seeds in the Final Four. But in a field of 68 teams, anything can happen. There's bound to be upsets all over. The question is, especially for betters: which lower seeds can pull off deep runs? The 12-5 first-round matchups typically provide the best range for realistic upset potential with betting value. If you're looking for some March Madness champion sleepers, the best 12 seed to pick in the first round, or a...