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Serie A: Napoli vs. Genoa – Confirmed line-ups

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Antonio Conte has decided to give a rest to Kevin De Bruyne, which means an opportunity for David Neres to impress as Napoli look to draw level with Roma at the top of the Serie A standings when they take on Genoa on Sunday afternoon.

Kick-off is due at 17.00 BST.

You can follow the action as it unfolds on the Football Italia Liveblog.

Antonio Conte’s side, who had won four Serie A matches in a row at the start of the season, suffered their first slip of the league campaign with a 2-1 defeat against Milan last weekend. The two sides currently sit level on points in the standings ahead of kick-off.

Genoa are without a win in Serie A in 2025-26, having lost three and drawn two at the start of the campaign, leaving them at the foot of the table on two points. They suffered a 3-0 defeat at home against Lazio last weekend.

Napoli are without key defenders in Alessandro Buongiorno, Amir Rrahmani plus full-back Pasquale Mazzocchi, as well as centre-forward Romelu Lukaku.

Genoa do not have Junior Messias, Maxwel Cornet or Nicolae Stanciu at their disposal against the Partenopei.

Kevin De Bruyne is given a rest by Conte, who has instead brought in winger David Neres. That means a likely siwtch to a 4-3-3, with Scott McTominay playing in a slightly more central role. The Scot has been lining up on the left of a 4-1-4-1 at the start of the 2025-26 season.

Napoli vs. Genoa: Confirmed line-ups

NAPLES, ITALY – OCTOBER 01: Antonio Conte SSC Napoli head coach during the UEFA Champions League 2025/26 League Phase MD2 match between SSC Napoli and Sporting Clube de Portugal at Stadio Diego Armando Maradona on October 01, 2025 in Naples, Italy. (Photo by Francesco Pecoraro/Getty Images)

Napoli (4-3-3): Milinkovic-Savic; Di Lorenzo, Juan Jesus, Beukema, Olivera; Lobotka, Anguissa, McTominay; Politano, Højlund, Neres.

Genoa (4-2-3-1): Leali; Sabelli, Marcandalli, Vasquez, Ellertson; Masini, Frendrup; Norton-Cuffy, Malinovskyi, Vitinha; Ekhator.

05-10-2025 17:00
MatchDay 6

Player statistic

1st half
    28' Alessandro Marcandalli
    33' Jeff Ekhator
(Assist: Brooke Norton-Cuffy)
    38' Ruslan Malinovskyi
2nd half
David Neres 55'    
Frank Anguissa 57'    
    63' Sebastian Otoa
Rasmus Højlund 75'    
Napoli
Genoa

Starting lineups

32
22
5
Defender
17
Defender
50'
31
Defender
99
Midfielder
8
Midfielder
68
Midfielder
44'
7
Attacker
82'
21
Attacker
50'
19
Attacker
82'
1
Goalkeeper
27
46'
15
22
Defender
20
Defender
76'
32
Midfielder
73
Midfielder
17
Midfielder
61'
21
Attacker
61'
9
Attacker
76'

Substitutes

1
Goalkeeper
20
Midfielder
26
Midfielder
30
70
Attacker
69
35
Defender
25
Goalkeeper
6
Midfielder
44'
37
50'
11
Midfielder
50'
27
Attacker
82'
3
82'
39
Goalkeeper
Midfielder
31
Goalkeeper
11
Midfielder
40
Attacker
3
Defender
30
Midfielder
76
34
Defender
46'
18
Attacker
61'
2
Midfielder
61'
29
Attacker
76'
23
Midfielder
76'