D-Xylose as a sugar complement regulates blood glucose levels by suppressing phosphoenolpyruvate carboxylase (PEPCK) in streptozotocin-nicotinamide-induced diabetic rats and by enhancing glucose uptake in vitro

Journal List Nutr Res Pract v.10(1); 2016 Feb PMC4742304 As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. Learn more: PMC Disclaimer | PMC Copyright Notice Nutr Res Pract. 2016 Feb; 10(1): 11–18. Published online 2015 Jun 19. doi:10.4162/nrp.2016.10.1.11PMCID: PMC4742304PMID: 26865911Eunju Kim,1 Yoo-Sun Kim,1 Kyung-Mi Kim,1 Sangwon Jung,2 Sang-Ho Yoo,3 and Yuri Kim1Author information Article notes Copyright and License information PMC DisclaimerAbstractBACKGROUND/OBJECTIVESType 2 diabetes (T2D) is more frequently diagnosed and is characterized by hyperglycemia and insulin resistance. D-Xylose, a sucrase inhibitor, may be useful as a functional sugar complement to inhibit increases in blood glucose levels. The objective of this study was to investigate the anti-diabetic effects of D-xylose both in vitro and stretpozotocin (STZ)-nicotinamide...