Povidone Iodine vs Chlorhexidine Gluconate for Preoperative Antisepsis—Reply

In Reply We agree with Dr Xie and colleagues that SSIs are caused by multiple contributing factors. This underlines the need for cluster-randomized trials (like our own), as contributing noncontrolled factors here are randomly distributed between groups. Of note, our study had an even distribution of allocations between the study sites and surgical specialties.