49ers RB Christian McCaffrey (knee) potentially out for season

(Photo credit: Tina MacIntyre-Yee/Democrat and Chronicle / USA TODAY NETWORK via Imagn Images)
San Francisco 49ers star running back Christian McCaffrey's season is in jeopardy after he sustained what is believed to be a posterior cruciate ligament injury in Sunday's 35-10 loss to the Buffalo Bills in Orchard Park, N.Y.

"I think potentially (it's season-ending)," 49ers head coach Kyle Shanahan said after the game. "I thi