Effect of Noninvasive Positive Pressure Ventilation on the Need for Endotracheal Intubation in COPD

This randomized clinical trial compares the effect of high-intensity noninvasive positive pressure ventilation (NPPV) vs low-intensity NPPV on the need for endotracheal intubation in patients with an acute exacerbation of chronic obstructive pulmonary disease and hypercapnia.