First successful synthesis of naphthocyclinones since their discovery 50 years ago

For the first time, beta- and gamma-naphthocyclinones were successfully synthesized in a laboratory, report scientists. By combining originally developed tactics and innovative strategies, researchers overcame big challenges in producing these complex molecules, which had eluded synthesis efforts for decades. This breakthrough contributes to our understanding of naphthocyclinone chemistry and opens doors to the development of compounds with potential applications in medicine and biotechnology.