Lifter Angles and Hemi Blocks

With a hemi I understand that there are two different lifter angles depending on the location of the cam. I believe a raised cam has a 48* lifter angle and a standard location cam has a 45* lifter angle. If this is so, then what happens if you put a 45* cam into a 48* block and degree the cam onto #1 cylinder or put a 48* cam into a 45* block. Is this possible????
If it is possible it would seem to be that one whole cylinder bank is going to be out of wack but other than not making a ton of...

Lifter Angles and Hemi Blocks