Achieving precise timing for DNA droplet division: A step towards artificial cells

A time-delay circuit enables precise control over the division of synthetic DNA droplets, which mimic biological Liquid-Liquid Phase Separation (LLPS) droplets found in cells. By utilizing a combination of microRNAs (miRNAs) and the enzyme RNase H, researchers have successfully regulated the timing of droplet division. This breakthrough paves the way for creating artificial cells with advanced functions, such as drug delivery and molecular computing.