Cardinals vs. Guardians MLB player props and odds - Sunday, September 22

Player prop bet options for Brendan Donovan, Jose Ramirez and others are available when the St. Louis Cardinals host the Cleveland Guardians at Busch Stadium on Sunday (at 2:15 p.m. ET).

Oddsmakers have tabbed the Cardinals (-111) as moneyline favorites versus the Guardians (-109). Cleveland (-1.5) is favored on the run line. Sportsbooks have set the over/under for this matchup at 7.5 runs.

St. Louis Cardinals prop bets today

Brendan Donovan player props

• Hits Prop: Over/Under 0.5 (Over Odds: -215)
• Runs Prop: Over/Under 0.5 (Over Odds: +150)
• RBI Prop: Over/Under 0.5 (Over Odds: +205)

For the Cardinals, Donovan has compiled 13 homers, 68 RBI, and 63 runs while putting up a .273/.339/.409 triple slash line in 622 PAs. His walk rate is 7.2%, and he’s striking out 12.4% of the time.

Brendan Donovan recent game stats

• vs. Guardians on Sept. 21: 0-for-4, 1 K
• vs. Guardians on Sept. 20: 0-for-3, 1 BB
• vs. Pirates on Sept. 19: 4-for-4, 2 RBI
• vs. Pirates on Sept. 18: 2-for-4, 2 R, 1 HR, 2 RBI, 1 K, 1 BB
• vs. Pirates on Sept. 17: 1-for-4, 1 K, 1 SB

Alec Burleson player props

• Hits Prop: Over/Under 0.5 (Over Odds: -250)
• Runs Prop: Over/Under 0.5 (Over Odds: +140)
• RBI Prop: Over/Under 0.5 (Over Odds: +205)

In 570 plate appearances, Alec Burleson is batting .269 with a .312 OBP and a .427 SLG. He has launched 21 dingers with 69 runs, 73 RBI, a 13.2% strikeout rate, and a 5.6% walk rate. Additionally, he’s swiped nine bases on 12 attempts.

Alec Burleson recent game stats

• vs. Guardians on Sept. 21: 0-for-1
• vs. Guardians on Sept. 20: 1-for-4, 1 R
• vs. Pirates on Sept. 19: 0-for-4, 2 K
• vs. Pirates on Sept. 18: 2-for-5, 1 R, 1 K
• vs. Pirates on Sept. 17: 0-for-0, 1 BB

Cleveland Guardians prop bets today

José Ramírez player props

• Hits Prop: Over/Under 0.5 (Over Odds: -240)
• Runs Prop: Over/Under 0.5 (Over Odds: +115)
• RBI Prop: Over/Under 0.5 (Over Odds: +170)

Ramirez has 37 home runs and 112 RBI this year for the Guardians, 109 runs scored, a strikeout rate of 11.9% and a walk rate of 8%, plus 40 steals on 47 attempts. His slash line is .276/.333/.523.

José Ramírez recent game stats

• at Cardinals on Sept. 21: 2-for-4, 1 R, 1 HR, 3 RBI
• at Cardinals on Sept. 20: 3-for-4, 1 R, 1 HR, 2 RBI, 1 SB
• vs. Twins on Sept. 19: 0-for-4, 1 R, 1 BB
• vs. Twins on Sept. 18: 1-for-4, 1 K
• vs. Twins on Sept. 17: 1-for-4, 1 K

Josh Naylor player props

• Hits Prop: Over/Under 0.5 (Over Odds: -205)
• Runs Prop: Over/Under 0.5 (Over Odds: +145)
• RBI Prop: Over/Under 0.5 (Over Odds: +160)

This season Josh Naylor has a slash line of .241/.318/.459, with 31 home runs and 105 RBI. He has scored 82 runs, and has strikeout and walk rates of 16.4% and 9.1%, respectively..

Josh Naylor Recent Game Stats

• at Cardinals on Sept. 21: 0-for-4
• at Cardinals on Sept. 20: 0-for-3, 1 BB
• vs. Twins on Sept. 19: 1-for-5, 1 R, 2 K
• vs. Twins on Sept. 18: 2-for-4, 3 R, 2 HR, 2 RBI, 1 K
• vs. Twins on Sept. 17: 0-for-4, 2 K

Cardinals vs. Guardians How to Watch, Starters

• When: Sunday, September 22, 2024 at 2:15 p.m. ET
• Where: Busch Stadium in St. Louis, Missouri
• How to Watch on TV: BSGL
• Livestream: Watch on Fubo!
• Cardinals Starter: Andre Pallante (7-8)
• Guardians Starter: Gavin Williams (3-10)