NFL Week 1 public betting: Bettors are predicting a Cardinals upset over the Bills

It’s not been a good start to the 2024 NFL season for anyone expecting underdogs to triumph in Week 1. Both the Kansas City Chiefs and Philadelphia Eagles won their openers as favorites on Thursday and Friday, respectively, and they both covered the spread too.

Now, we go into the first Sunday of the year with a few more favorites looking to spoil some bets. That includes the Buffalo Bills, whose seven-point spread against the Arizona Cardinals makes them the second-largest favorites of the week.

That hasn’t stopped bettors from picking the other side at BetMGM. Here are the splits for that game and the others Week 1.