Clinical Test for Calcium Release Deficiency Syndrome?

On any cardiac electrophysiology service, the evaluation of survivors of resuscitated cardiac arrest is commonplace, often resulting in the placement of an implantable cardioverter-defibrillator, but without a satisfactory answer regarding the cause of the cardiac arrest. When a young and otherwise healthy family member of such a patient then dies suddenly, it is both tragic and frustrating, particularly if the family member was deemed in good health after a thorough cardiovascular assessment. Sadly, such a story has been the reality for more than 1 person with calcium release deficiency syndrome (CRDS).