C-reactive Protein: A Prognostic Indicator

Journal List Int J Appl Basic Med Res v.7(2); Apr-Jun 2017 PMC5441268 As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. Learn more: PMC Disclaimer | PMC Copyright Notice Int J Appl Basic Med Res. 2017 Apr-Jun; 7(2): 83–84. doi:10.4103/ijabmr.IJABMR_63_17PMCID: PMC5441268PMID: 28584735Mandeep KaurAuthor information Copyright and License information PMC DisclaimerC-reactive protein (CRP) is a serum acute phase reactant and a valuable inflammatory biomarker in various clinical conditions. It was first discovered by Tillett and Francis (1930) in the serum of patients with pneumonia but was isolated in 1941.[1] CRP derives its name due to ability of the CRP to react with C-polysaccharide isolated from pneumococcal cell walls. The CRP gene is located on the first chromosome. It is an inducible protein which is secreted mainly by hepatocytes in res...