Imaging lifespan brain structural growth: From region, to connectome, to gradient

by Xing Qian, Juan Helen Zhou

Throughout human life, the brain undergoes intricate structural changes that support cognition. A study in PLOS Biology introduces new avenues for depicting the trajectory of the brain morphometric connectome and its underlying genetic and molecular mechanisms. During development and aging the brain undergoes intricate structural changes. This Primer explores the implications of a new study in PLOS Biology, which provides a detailed characterization of how the brain’s morphometric organization changes throughout the human lifespan to support cognition.