A mitochondria-to-nucleus regulation mediated by the nuclear-translocated mitochondrial lncRNAs
by Jia Li, Ruoling Bai, Yulian Zhou, Xu Song, Ling Li
A bidirectional nucleus-mitochondria communication is essential for homeostasis and stress. By acting as critical molecules, the nuclear-encoded lncRNAs (nulncRNAs) have been implicated in the nucleus-to-mitochondria anterograde regulation. However, role of mitochondrial-derived lncRNAs (mtlncRNAs) in the mitochondria-to-nucleus retrograde regulation remains elusive. Here, we identify functional implication of the mtlncRNAs MDL1AS, lncND5 and lncCyt b in retrograde regulation. Читать дальше...