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Новости за 09.01.2025

Refining fine-mapping: Effect sizes and regional heritability

Plos.org 

by Christian Benner, Mahajan Anubha, Matti Pirinen

Recent statistical approaches have shown that the set of all available genetic variants explains considerably more phenotypic variance of complex traits and diseases than the individual variants that are robustly associated with these phenotypes. However, rapidly increasing sample sizes constantly improve detection and prioritization of individual variants driving the associations between genomic regions and phenotypes. Therefore, it is useful... Читать дальше...

Eight quick tips for biologically and medically informed machine learning

Plos.org 

by Luca Oneto, Davide Chicco

Machine learning has become a powerful tool for computational analysis in the biomedical sciences, with its effectiveness significantly enhanced by integrating domain-specific knowledge. This integration has give rise to informed machine learning, in contrast to studies that lack domain knowledge and treat all variables equally (uninformed machine learning). While the application of informed machine learning to bioinformatics and health informatics datasets has become more seamless... Читать дальше...

Multi-region infectious disease prediction modeling based on spatio-temporal graph neural network and the dynamic model

Plos.org 

by Xiaoyi Wang, Zhen Jin

Human mobility between different regions is a major factor in large-scale outbreaks of infectious diseases. Deep learning models incorporating infectious disease transmission dynamics for predicting the spread of multi-regional outbreaks due to human mobility have become a hot research topic. In this study, we incorporate the Graph Transformer Neural Network and graph learning mechanisms into a metapopulation SIR model to build a hybrid framework, Metapopulation Graph Transformer Neural Network (M-Graphormer)... Читать дальше...

No Fannies In The Seats: ACC Teams With Poor Attendance This Season

Duke Basketball Report 

SYRACUSE, NEW YORK - JANUARY 10: Donald Hand Jr. #13 of the Boston College Eagles controls the ball against the Syracuse Orange during the first half at the JMA Wireless Dome on January 10, 2024 in Syracuse, New York. Syracuse won 69-59. | Photo by Rich Barnes/Getty Images

In fairness, most of these teams haven’t played well enough to interest fans very much.

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Fact check: What really happened with the Pacific Palisades water hydrants? - LAist

Top Stories (us) - Google News (ru) 

  1. Fact check: What really happened with the Pacific Palisades water hydrants?  LAist
  2. Interactive 3D map shows Eaton Fire perimeter, evacuation areas  KTLA Los Angeles
  3. At least 5 dead as thousands flee raging wildfires in Los Angeles area: Live updates  CNN
  4. Firefighters make progress slowing wildfires while Los Angeles grapples with scope of devastation  The Associated Press

Lukashevich: China is eager to study Belarus’ culture

BelTA (en) 

“Mentality, national character, historical heritage, creative resources of our peoples are most clearly manifested and expressed in culture. Interest to get to know each other better is mutual," Belarus' First Deputy Minister of Foreign Affairs Sergei Lukashevich said.

Amazon Is Selling Its Adtech to Other Retailers, Taking Direct Aim at Firms Like Criteo

Adweek.com 

Amazon built a $50 billion ad business by selling sponsored placements on its website and app. Now, the ecommerce giant wants to do the same for other retailers. Today at CES, Amazon Ads announced a new ad product called Amazon Retail Ad Service, allowing retailers to use Amazon's tools to sell product ads appearing on...