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Новости за 06.01.2025

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IAI Coletivo _ Atelier / IAI Coletivo

Archdaily.com 
En

Located in Aves, in the municipality of Santo Tirso, Porto, the Atelier occupies one of the spaces in the commercial gallery of a building from the 1980s situated in the village's urban center. The main access to the Atelier is through the external gallery that surrounds the building. The space is highlighted by its abundance of natural light and its elevated location above the street, providing a calm and welcoming environment.

Bifurcation analysis of an influenza A (H1N1) model with treatment and vaccination

Plos.org 
En

by Kazi Mehedi Mohammad, Asma Akter Akhi, Md. Kamrujjaman

This research uses numerical simulations and mathematical theories to simulate and analyze the spread of the influenza virus. The existence, uniqueness, positivity, and boundedness of the solution are established. We investigate the fundamental reproduction number guaranteeing the asymptotic stability of equilibrium points that are endemic and disease-free. We also examine the qualitative behavior of the models. Using the Lyapunov method... Читать дальше...

Expanding first-line options for depression: Protocol of a pragmatic comparative effectiveness trial of yoga vs. behavioral activation (the COMPARE study)

Plos.org 
En

by Louisa G. Sylvia, Andrew M. Busch, Dustin J. Rabideau, Alexandra Gold, Suzanne C. Danhauer, Heather T. Schatten, Douglas Katz, Lauren M. Weinstock, Jennifer Dahne, Sabine P. Schmid, Zainab Soetan, Roberta Tovey, Kedie Pintro, Adrienne Kvaka, Antonietta Alvarez Hernandez, Ingrid Hsu, Alba Melendez, Melissa Adkins-Hempel, Angela Grubb, Odalys Lozado, Atefeh Alavi Fili, Giuliana Chau, Lisa A. Uebelacker

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The urban carbon unlocking effect of digital infrastructure construction: A spatial difference-in-difference analysis from “Broadband China” pilot policy

Plos.org 
En

by Liang Guo, Lijing Chen, Zhen Yang

As the foundation and cornerstone of the digital economy, digital infrastructure construction is an indispensable engine for realizing China’s energy-saving and emission-reduction, innovation-driven and low-carbon transformation and development. Investigating the carbon unlocking effect of digital infrastructure construction might hasten the achievement of the dual-carbon goal and the “win-win” scenario of environmental protection and economic growth. However... Читать дальше...

Construction of management tools for early warning of prevacuum steam sterilization failure

Plos.org 
En

by Xin Zhao, Ting Liu, Ning Ma, Ran Wang, Ying Li, Tong Shen

Objective

The aim of this study is to develop a set of management tools for early warning of steam sterilization failure, including a failure risk checklist and a calculation model for assessing early sterilization failure risk, and to verify the early warning effectiveness of the management tools through check experiment.

Methods

This study included two stages. The first stage involved the construction of a failure risk... Читать дальше...

Chlorogenic acid inhibits NLRP3 inflammasome activation through Nrf2 activation in diabetic nephropathy

Plos.org 
En

by Liping Bao, Yuhan Gong, Wenji Xu, Jun Dao, Jinjin Rao, Haihui Yang

Diabetic nephropathy (DN) is the single largest cause of end-stage renal disease (ESRD). Inflammation reaction mediated by NLRP3 inflammasome and Nrf2-related oxidative stress have been considered to play a very important role in the progress of diabetic nephropathy (DN). Effective drugs for the treatment of diabetic nephropathy still need to be explored. Chlorogenic acid (CGA) is a kind of polyphenol with a Nrf2 activation property widely existed in nature. Читать дальше...