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Новости за 24.12.2024

The Tobacco Industry Has No Business Funding CME

Jamanetwork.com 

This Viewpoint explores tobacco industry–funded continuing medical education and concerns regarding the precedents this funding sets in relation to commercial bias and influence and conflicts of interest.

Individualized Recommendations for Acute Kidney Injury

Jamanetwork.com 

This randomized clinical trial tested whether recommendations from a kidney action team tailored to individual patients presenting with acute kidney injury would improve clinical outcomes, kidney function, and mortality.

Postmarketing Surveillance of Inferior Vena Cava Filters

Jamanetwork.com 

This prespecified, retrospective observational cohort study examines the trends in inferior vena cava filter insertion and retrieval for the prevention of venous thromboembolism among US Medicare beneficiaries.

Enhancing Medical Device Postmarketing Safety Surveillance

Jamanetwork.com 

The 1976 Medical Device Amendments granted the US Food and Drug Administration (FDA) regulatory authority over medical devices. The FDA’s regulatory review requirements are intended to correspond to the amount of information needed to provide “reasonable assurance of device safety and effectiveness” and establish a 3-tiered system for classifying devices based on their risk profile (low, moderate, and high) with a corresponding degree of evidence required for review. Low-risk devices are typically only subject to general controls (eg... Читать дальше...

Obesity Prevention at an Early Age

Jamanetwork.com 

In recent decades obesity rates among US adults has climbed from 14% to 40%, with correspondingly high rates of obesity in children. Being overweight or obese in childhood is highly predictive of cardiometabolic disease in adults. The American Heart Association recently projected that by 2050 the adult prevalence of diabetes will increase from 16.3% to 26.8% and obesity from 43.1% to 60.6%, with obesity rates in children predicted to increase from 20.6% in 2020 to 33.0% in 2050 and with nearly 60%... Читать дальше...

Gap Years—Unbridled Good or Unwarranted Cost?

Jamanetwork.com 

This Viewpoint discusses the increasing popularity of taking a gap year between college and medical school and raises questions about the perceived necessity of this trend, its financial and other costs, and the potential disadvantage it may pose to underrepresented minority applicants.

Medical Education’s Learning Opportunity

Jamanetwork.com 

This Viewpoint discusses the importance of teaching health policy to medical students so they can be informed on the everyday policy issues that patients may ask them about or for which their specialty societies may ask them to lobby.

Legal Protections for Biologics vs Small-Molecule Drugs in the US

Jamanetwork.com 

This Special Communication analyzes and compares development times, clinical trial success rates, research and development costs, patent protection, market exclusivity periods, revenues, and treatment costs of biologics with small-molecule drugs.

Graduate Medical Education, 2023-2024

Jamanetwork.com 

This Appendix presents 2023 National GME Census data detailing the numbers and types of ACGME-accredited training programs and the residents and fellows in them.

The Ghazal and Melancholy

Jamanetwork.com 

The ghazal is an ancient poetic form thought to have originated in 7th-century Arabic, and which later spread to medieval Persia via the work of the famed mystical poets Rumi and Hafez. In modern times, it is frequently performed in song in countries such as Iran and Pakistan, and has been brought into English by a number of contemporary poets, perhaps most notably by Agha Shahid Ali. The form typically consists of long-lined couplets with a repeated end word or phrase concluding each; the final... Читать дальше...

Heart Failure: A Ghazal

Jamanetwork.com 

In mind, a world comes to life, one not to be revived except in mind, the end on its dauntless way, little else remaining to ponder.

Tirzepatide for Weight Reduction in Chinese Adults With Obesity—Reply

Jamanetwork.com 

In Reply We appreciate the letter from Ms Chen and colleagues about our article. First, differences in intensity of lifestyle interventions can affect weight reduction efficacy, with initial weight loss at 1 year ranging from −2% to −9%. Chen and colleagues ask about the efficacy of lifestyle interventions in our trial compared with results from the DIADEM-I and Look AHEAD trials, both of which included intensive lifestyle interventions. Our trial, similar to others investigating the efficacy and safety of antiobesity medications... Читать дальше...

Tirzepatide for Weight Reduction in Chinese Adults With Obesity

Jamanetwork.com 

To the Editor A recent study reported that once-weekly treatment with tirzepatide can effectively lead to weight reduction. However, we have several concerns about this article. First, the effect of lifestyle in this study requires further exploration. Among patients receiving tirzepatide, there was a weight reduction of 11.3% to 15.1% compared with placebo. All patients underwent lifestyle intervention, and after 52 weeks of treatment, the placebo group had only a 2.3% reduction in body mass. Although the populations in the studies differed... Читать дальше...