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Новости за 16.12.2024

Treating prostate cancer with novel platinum complex via targeting androgen receptor signaling

Sciencedaily.com 

Prostate cancer, especially in advanced stages such as castration-resistant prostate cancer, is challenging to treat. Traditional therapies targeting androgen receptor (AR) signaling have limited efficacy. In a recent study, researchers investigated the potential of azolato-bridged dinuclear platinum(II) complexes, particularly 5-H-Y, as promising alternatives. Their findings highlight the complex's ability to inhibit AR signaling and induce cell death in prostate cancer cells, providing a new avenue for prostate cancer treatment.

New research about drought impacts on wildlife can inform conservation strategies

Sciencedaily.com 

New research shows that many wildlife species in the U.S., like the endangered giant kangaroo rat, will face much more frequent and severe droughts in the future. By 2050-2080, year-long droughts could happen almost five times as often, and three-year droughts almost seven times as often compared to past decades. These changes will require animals to adapt significantly. Scientists have identified areas with high biodiversity and high risk that can help managers focus attention for conservation efforts. Читать дальше...

Elucidating the neural mechanisms of stress-induced cardiovascular responses

Sciencedaily.com 

The lateral habenula is a brain region associated with behavioral changes and autonomic responses during psychological stress. Researchers at the University of Tsukuba have identified the involvement of the dopaminergic system in the cardiovascular responses triggered by neuronal excitation in the lateral habenula. They further determined that the ventral tegmental area of the midbrain, which is the origin of dopamine neurons, plays a mediating role in this response.

Bioengineered yeast microbes as targeted drug delivery systems

Sciencedaily.com 

Researchers have developed a groundbreaking way to engineer yeast (Saccharomyces cerevisiae) to create microbial communities that can perform complex tasks and self-regulate their composition in response to external signals.

Christmas comes early thanks to DFC Community team

Dartford FC 

DFC Community Team visited 12 schools to deliver some Christmas cheer over the past two weeks. Christmas gift hampers were presented to Dartford schools as a thank-you for hosting DFC coaches and keeping their pupils highly-active. The boxes – featuring cheese, chutney, chocolate and more – were given to teachers by DFC Community coaches. Each […]

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Pubs introducing 'Guinness Ration Cards' after unprecedented surge in demand - Metro.co.uk

Sports - Google News (uk) 

  1. Pubs introducing 'Guinness Ration Cards' after unprecedented surge in demand  Metro.co.uk
  2. How Gen Z ruined Guinness  The Spectator
  3. Guinness stocks run dry as pubs forced to ration pints  The Independent
  4. Why Some British Pubs Are Running Out of Guinness  The New York Times
  5. Is your local out of Guinness? London's best pubs still pouring pints  Evening Standard

How a Conversion Optimization Consultant Can Boost Your Sales

List.ly 

A Listly List - In today’s competitive digital landscape, businesses in Houston and beyond must focus on not just attracting visitors to their websites, but also converting them into loyal customers. That’s where a conversion optimization consultant comes in. These specialists work to maximize the effectiveness of your website, ensuring that every visitor has the best possible chance of becoming a paying customer. In this blog, we'll explore how a conversion optimization consultant can boost your sales by fixing website errors... Читать дальше...

Bloated Man Recalls Halcyon Days Of 7 Oreos Ago

TheOnion.com 

LEXINGTON, KY—Clutching his stomach and describing his nostalgia for an era now passed, 36-year-old man Steven Dewey sat down with reporters this week and recalled his halcyon days of seven Oreos ago. “Ah, to be at the beginning of the pack with a whole sleeve still ahead of you,” said Dewey, appearing wistful as he […]

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Friday Night Dinner spin-off axed after just one series

TheSun.co.uk 

A FRIDAY Night Dinner spin-off has been axed after just one series.

An Amazon free streaming service announced it will no longer serve up extra helpings of the show Dinner With The Parents.

Channel 4The series charts the ups and downs of the Langar family, but it was a huge flop in the US[/caption] Channel 4The original Friday Night Dinner featured Tom Rosenthal as Jonny, Paul Ritter as Martin and Simon Bird as Adam.[/caption] Amazon/FreeveeDinner With The Parents on Amazon... Читать дальше...

Atrial fibrillation: A review

Sciencedaily.com 

In the U.S., atrial fibrillation (AF), a heart condition that causes an irregular heartbeat in the upper chambers of the heart, affects up to one in three people in their lifetime. Significant complications associated with this condition include ischemic stroke, heart failure, myocardial infarction, chronic kidney disease, dementia and mortality. In a new review article scientists summarize the current evidence regarding the epidemiology, pathophysiology, diagnosis and management of AF.