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Новости за 13.12.2024

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Rapid assessment of noma: Reporting on forgotten and neglected disease in Ethiopia

Plos.org 
En

by Wendemagegn Enbiale

Background

Noma is a rapidly progressing, invasive, and debilitating orofacial disease that primarily affects the most vulnerable and marginalised populations worldwide. The highest- risk group includes pre-school children, exposed to other risk factors, such as malnutrition and poverty-related diseases. Since 2010, Ethiopia has reported an increasing number of noma cases, primarily identified through medical missions. Data on the disease burden and epidemiology are... Читать дальше...

Relevance of reporting leprosy related disability at the completion of multi drug therapy: A 5-year retrospective analysis of disability in persons affected by leprosy at ALERT Hospital Ethiopia

Plos.org 
En

by Bereket Abebayehu Tegene, Thomas Asfaw Atnafu

Background

Leprosy is one of the neglected tropical diseases associated with significant morbidity in endemic regions. It causes disability affecting the daily activities and social participation of affected individuals. Understanding the prevalence and trend of leprosy-related disability throughout the world and the accuracy of disability data counted by WHO is crucial in guiding efforts to be made towards the targets set by WHO to be achieved by 2030. Читать дальше...

Presence of Trypanosoma cruzi (TcI) in different tissues of Didelphis virginiana from the metropolitan area of Merida, southeastern Mexico: Epidemiological relevance and implications for non-vector transmission routes

Plos.org 
En

by Pedro Pablo Martínez-Vega, Marian Rivera-Pérez, Gabrielle Pellegrin, Antoine Amblard-Rambert, Jorge Andrés Calderón-Quintal, Christian Barnabé, Christian Teh-Poot, Hugo Ruiz-Piña, Antonio Ortega-Pacheco, Etienne Waleckx

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TransferGWAS of T1-weighted brain MRI data from UK Biobank

Plos.org 
En

by Alexander Rakowski, Remo Monti, Christoph Lippert

Genome-wide association studies (GWAS) traditionally analyze single traits, e.g., disease diagnoses or biomarkers. Nowadays, large-scale cohorts such as UK Biobank (UKB) collect imaging data with sample sizes large enough to perform genetic association testing. Typical approaches to GWAS on high-dimensional modalities extract predefined features from the data, e.g., volumes of regions of interest. This limits the scope of such studies to... Читать дальше...

Advanced vision transformers and open-set learning for robust mosquito classification: A novel approach to entomological studies

Plos.org 
En

by Ahmed Akib Jawad Karim, Muhammad Zawad Mahmud, Riasat Khan

Mosquito-related diseases pose a significant threat to global public health, necessitating efficient and accurate mosquito classification for effective surveillance and control. This work presents an innovative approach to mosquito classification by leveraging state-of-the-art vision transformers and open-set learning techniques. A novel framework has been introduced that integrates Transformer-based deep learning models with comprehensive... Читать дальше...

Tree polynomials identify a link between co-transcriptional R-loops and nascent RNA folding

Plos.org 
En

by Pengyu Liu, Jacob Lusk, Nataša Jonoska, Mariel Vázquez

R-loops are a class of non-canonical nucleic acid structures that typically form during transcription when the nascent RNA hybridizes the DNA template strand, leaving the non-template DNA strand unpaired. These structures are abundant in nature and play important physiological and pathological roles. Recent research shows that DNA sequence and topology affect R-loops, yet it remains unclear how these and other factors contribute to R-loop formation. Читать дальше...

Deutsch Elevates Four Department Leaders to its C-Suite

Adweek.com 
En

Amidst the news of Omnicom Group and Interpublic Group's (IPG) merger, IPG agency Deutsch announced it is promoting four department leaders to its C-suite. Ivan Perez-Armendariz will become chief digital officer; Heide Peper Hays will become chief data and intelligence officer; Diego de la Maza will become chief production officer; and Lauren Tetuan will become...