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Новости за 03.12.2024

Diversity Action Plans: Promise and Perils

Jamanetwork.com 

This Viewpoint discusses the US Food and Drug Administration’s authority to require drug and device sponsors to submit diversity action plans and policy gaps that limit the organization’s ability to achieve demographic representation in clinical trials.

Diversity Action Plans in Clinical Trials

Jamanetwork.com 

This Viewpoint discusses the US Food and Drug Administration’s upcoming mandate on diversity actions plans for trial sponsors and the importance of developing accountability mechanisms to monitor those plans.

Effect of Tele-ICU on Clinical Outcomes of Critically Ill Patients

Jamanetwork.com 

This parallel cluster randomized clinical trial examines the effect of daily multidisciplinary rounds conducted via telemedicine by a board-certified intensivist on length of stay in the intensive care unit in critically ill adult patients in Brazil.

Screening Frequency and Spontaneous Breathing Trial Techniques

Jamanetwork.com 

This randomized clinical trial compares the effects of screening frequency (once-daily vs more frequent screening) and spontaneous breathing trial techniques (pressure-supported vs T-piece spontaneous breathing trial) on the time to successful extubation among critically ill adults who required invasive mechanical ventilation.

Evaluating Complex Technological Innovations in Critical Care

Jamanetwork.com 

The benefits of the intensive care unit (ICU) for delivering high-quality care and improving survival for critically ill patients are primarily due to the people who work there—the specialized physicians, nurses, and other health care professionals who comprise the interprofessional critical care team. Yet, over the last century, the field is increasingly defined not by people, but by technology—mechanical ventilators, invasive monitors, and, most recently, artificial intelligence (AI) to predict outcomes and guide therapy. Читать дальше...

Ventilator Weaning Strategies

Jamanetwork.com 

Weaning of mechanical ventilation is a critical aspect of care for patients in intensive care units (ICUs). The process of weaning involves the gradual reduction in intensity of ventilatory support sufficient to allow the patient to resume spontaneous breathing. This transition is crucial because prolonged mechanical ventilation can lead to complications that affect survival and the quality of survival. Spontaneous breathing trials (SBTs) and screening for readiness to wean are central to this process... Читать дальше...

Buprenorphine/Naloxone vs Methadone for the Treatment of Opioid Use Disorder

Jamanetwork.com 

This population-based retrospective cohort study uses linked health administrative databases to assess the risk of treatment discontinuation and mortality among adults in British Columbia, Canada, receiving buprenorphine/naloxone vs methadone for the treatment of opioid use disorder.

Health and the 2024 US Election

Jamanetwork.com 

The outcome of the 2024 US election will undoubtedly affect patient and community health, along with the health care delivery system, in a multitude of ways. In response to a call for articles on August 18, 2023, by the JAMA Network, articles have been published in JAMA and multiple JAMA Network journals addressing many of the health and health care issues at stake in the election. As the November 5, 2024, election date draws near, this Editorial provides a summary of key aspects of the JAMA publications. Читать дальше...

Peptic Ulcer Disease

Jamanetwork.com 

This narrative review article covers current evidence regarding the diagnosis and treatment of peptic ulcer disease.

Kidney Transplant Outcomes From Donors Who Received Dialysis—Reply

Jamanetwork.com 

In Reply In response to specific points raised by Drs Yang and Tebbutt, kidney donors in our study received in-center hemodialysis during their hospitalization at the time of donation. Warm ischemic time was calculated as the number of minutes from withdrawal to cross-clamp time in donors after cardiac death. The donors after cardiac death who had undergone dialysis (n = 35) had similar warm ischemic time (median, 28 minutes [IQR, 22.5-34.0 minutes]) vs the 35 donors after cardiac death who had not undergone dialysis (median... Читать дальше...

Kidney Transplant Outcomes From Donors Who Received Dialysis

Jamanetwork.com 

To the Editor Kidney transplant offers the best long-term outcomes for patients with end-stage kidney disease. A recent article examined the viability of kidneys from deceased donors who underwent dialysis before donation, and found a higher incidence of delayed graft function in these recipients, but no differences in graft failure or mortality compared with recipients of kidneys from donors who did not undergo dialysis. Several aspects of the study warrant further exploration to better understand... Читать дальше...

a fall

Jamanetwork.com 

against the trunk, lying head back to get the count of branches compressed and displaced i can’t stand up through the dome thinning out to spokes of a kaleidoscope turning back and forth equally in ruin

Associations of Internal Medicine Residency Ratings and Certification Examination Scores With Patient Outcomes—Reply

Jamanetwork.com 

In Reply In response to the Letters about our recent article, we agree with Dr Brateanu and colleagues about the need for ongoing research assessing changes in milestone ratings, which were revised after our study period, and assessing the usefulness of ITEs. Similarly, the lack of granularity of milestone ratings may have contributed to their lack of associations with outcomes, which could be addressed by milestone updates. However, we found similar associations when applying more and less granular rating measures. Читать дальше...

Associations of Internal Medicine Residency Ratings and Certification Examination Scores With Patient Outcomes

Jamanetwork.com 

To the Editor A recent study found that among newly trained hospitalists, higher certification examination scores were associated with improved outcomes for hospitalized Medicare beneficiaries, whereas residency milestone ratings did not show a similar association. These are thought-provoking findings that prompt reflection on how residency programs and their clinical competency committees evaluate and interpret residents’ performance and readiness for unsupervised practice.

A Patient With Headaches and Peripheral Vision Loss

Jamanetwork.com 

A 30-year-old nulliparous woman with obesity and history of migraines and depression had 1 month of daily headaches, transient bilateral visual blurring, persistent vision loss in the temporal region of one eye, pulsatile tinnitus, and mild bilateral papilledema. What is the diagnosis and what would you do next?

Osteophyte

Jamanetwork.com 

In this narrative medicine essay, a medical student discusses the challenges of conveying her grandmother’s feelings to her physician while serving as an interpreter for her grandparents’ clinic visits.

Medical Expert Testimony

Jamanetwork.com 

Although there are earlier references, both historical and biblical, to the utilization of medical knowledge in relation to public health and to legal matters, the definitive connection between law and medicine may perhaps be dated from the publication of the Codes of Justinian, about 530 A. D. These contained provisions requiring expression of medical opinion in certain legal cases. Between 1500 and 1525, almost all of the principalities and other subdivisions of Central Europe adopted laws requiring... Читать дальше...

Working With Medical Interpreters

Jamanetwork.com 

This JAMA Insights discusses the important role that interpreters play in facilitating communication between patients with limited English-language proficiency and their health care team and provides steps that can be taken to improve communication with remote interpreters for patients.