Новости за 19.11.2024

Retinoblastoma, a rare but aggressive eye cancer in infants and young children, accounts for 2% to 4% of pediatric malignancies globally, with an incidence rate ranging from 1 in 20 000 to 1 in 15 000 children. Approximately 8000 new cases are reported annually across the globe, of which more than 1000 are reported in China. Notably, regions with the highest prevalence, such as Asia and Africa, have the highest mortality rates, ranging from 40% to 70%, in stark contrast with the 3% to 5% mortality rate in high-income countries. Читать дальше...

When you hear the cancer doctor we just met read the biopsy results from your PET scan, the issues leading up to this moment, directly off an Epic chart with precision, wonder: then

This pooled cross-sectional study explores prescribing rates for glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter 2 inhibitors among US patients with type 1 diabetes.

This JAMA Insights examines the treatment and rising prevalence of anal cancer in the US in high-risk groups, including people with HIV and immunosuppression associated with solid organ transplant.

In this narrative medicine essay, a pediatric oncology fellow who weaves storytelling into her practice to help patients process their illness describes how a young boy’s mother captures his story through photography.

This JAMA Patient Page describes allergic rhinitis and its risk factors, diagnosis, and treatment.

In Reply Our study adjusted the FIT cutoff to yield the same overall positivity rate as reported for the mt-sRNA test (17%) to enhance comparability of diagnostic performance of both tests. Below we address each of the 3 points made by Drs Yang and Ma.

To the Editor We read with interest the recent study that compared the fecal immunochemical test (FIT) positivity threshold vs multitarget stool RNA (mt-sRNA) testing for colorectal cancer screening. However, we have concerns regarding the study methodology and the capability of FIT to fully replace the mt-sRNA panel.

Some of the most dramatic chapters in the history of medicine deal with the development of surgery. “A good surgeon must have an eagle’s eye, a lion’s heart, a lady’s hand.” Thus runs the old English proverb, formulated in the days before anesthetics banished pain and antiseptics averted the horrors of wound infection. Today no large part of the body is destined to remain free from surgical approach. The abdomen, thorax and cranium have already been invaded by the trained surgeon with eminent success in the relief of a variety of maladies. Читать дальше...

This JAMA Clinical Guidelines Synopsis summarizes the Wilderness Medical Society’s 2024 recommendations on prevention, diagnosis, and treatment of acute altitude illness.

The Original Investigation titled “Risankizumab for Ulcerative Colitis: Two Randomized Clinical Trials,” published on July 22, 2024, has been updated to fix the affiliation for Nobuo Aoyama and add the names of investigators (Federico Arguelles Arias, Toshiyuki Endo, Jill Gaidos, Jee Hyun Kim, Albert Pirmagomedov, and Nikolaos Viazis) missing from the original version of Supplement 3. This article was corrected online.

Listen to the JAMA Editor’s Summary for an overview and discussion of the important articles appearing in JAMA.

This Medical News article discusses the reasons behind the resurgence of pertussis in the US and elsewhere this year.

This Medical News article discusses new research on global trends in nearsightedness, possible ways to prevent and treat it, and calls to classify it as a disease.

Too few patients with abnormal urine protein dipstick test results receive the recommended follow-up with albumin to creatinine ratio (ACR) testing to assess albuminuria, a risk factor for chronic kidney disease, according to new research published in the Annals of Internal Medicine.

Bright light therapy is often used to treat seasonal depressive disorder, but the results of a recent trial in JAMA Psychiatry suggest that its benefits may not extend to treatment of depressive disorders in hospitalized adolescents.

Adding to decades of evidence on the negative effects of the historical discriminatory practice called redlining, a new study finds that those who lived in redlined neighborhoods in 1940 had a lower life expectancy than those who did not.

The US Food and Drug Administration (FDA) recently approved a new treatment for schizophrenia that relies on a novel mechanism of action. Oral xanomeline and trospium chloride, marketed as Cobenfy, is the first antipsychotic drug authorized to treat the disease via cholinergic receptors instead of dopamine receptors, which has historically been the therapeutic pathway.

Although most measles cases in England occur among unvaccinated individuals, the proportion of cases among those who were fully vaccinated with 2 doses of the measles, mumps, and rubella (MMR) vaccine increased between 2010 and 2019.

The American Academy of Pediatrics (AAP) released its first clinical guidance on prescribing opioids for outpatient acute pain management to youth. Although it cautions against the dangers of rising opioid use disorder among children and teens, it also notes that a decrease in opioid prescription rates may leave some youth with pain that is not adequately treated.

Mouth taping is a sleep technique that has been promoted widely across social media. Although mouth breathing during sleep is associated with severity of obstructive sleep apnea (OSA), research recently published in JAMA Otolaryngology–Head & Neck Surgery suggests that it may be important to maintain airflow in some patients with nasal obstruction.

The Administration for Strategic Preparedness and Response, an agency within the US Department of Health and Human Services, has announced the reopening of COVIDTests.gov to deliver free COVID-19 tests to households. The agency’s investment of $600 million to 12 domestic test manufacturers will supply 200 million home tests.

RMT has criticised the decision to reprivatise the Elizabeth Line after GTS Rail Operations Limited won a bid to run the London rail service.

The women’s boxing rematch was one for the ages.

Date: 11/19/2024
Player: Patrik Koch (D)
From: Tucson Roadrunners
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