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Новости за 04.11.2024

Harnessing the optimization of enzyme catalytic rates in engineering of metabolic phenotypes

Plos.org 

by Zahra Razaghi-Moghadam, Fayaz Soleymani Babadi, Zoran Nikoloski

The increasing availability of enzyme turnover number measurements from experiments and of turnover number predictions from deep learning models prompts the use of these enzyme parameters in precise metabolic engineering. Yet, there is no computational approach that allows the prediction of metabolic engineering strategies that rely on the modification of turnover numbers. It is also unclear if modifications of turnover numbers... Читать дальше...

Apoptotic extracellular vesicles carrying Mif regulate macrophage recruitment and compensatory proliferation in neighboring epithelial stem cells during tissue maintenance

Plos.org 

by Safia A. Essien, Ivanshi Ahuja, George T. Eisenhoffer

Apoptotic cells can signal to neighboring cells to stimulate proliferation and compensate for cell loss to maintain tissue homeostasis. While apoptotic cell-derived extracellular vesicles (AEVs) can transmit instructional cues to mediate communication with neighboring cells, the molecular mechanisms that induce cell division are not well understood. Here, we show that macrophage migration inhibitory factor (Mif)-containing AEVs regulate... Читать дальше...

Gameday: Raptors @ Nuggets, November 4

Raptors Republic 

Raptors aim for their first consecutive wins

The post Gameday: Raptors @ Nuggets, November 4 first appeared on Raptors Republic.

Why Ilana Kaplan Still Thinks There's Hope for Romantic Comedies

GQ.com 

It's one of the most crowd-pleasing film genres of all time—and despite the success of films like Anyone But You and The Idea of You, Hollywood has all but given up on it. But the author of Nora Ephron at the Movies, a new book on the creator of When Harry Met Sally, believes that can change.

Here’s How to Watch Election Night 2024 Coverage

Adweek.com 

The biggest night of America's political calendar is upon us. On Nov. 5, millions of viewers around the country to tune in to see which presidential candidate will enter the Oval Office in January: Vice President Kamala Harris or former President Donald Trump. With 2024's contest polling so closely, the outcome of the election will...

These Cars Have The Coolest Badges And Logos

Jalopnik.com 

Badges and logos are supposed to be simple symbols or graphics that are meant to represent something else, and in the wonderful world of capitalism, brand recognition is important. Having an easily identifiable logo means consumers are subconsciously aware of a company’s presence. Last week, we asked you lot what cars…

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Election Day Vital Voters’ Guide 2024: What to know in NY, NJ

Pix11.com 

NEW YORK (PIX11) – Voters across New York and New Jersey will cast their ballot in federal, state, and local elections on Tuesday. While the race between Vice President Kamala Harris and former President Donald Trump has dominated headlines for months, voters in both states will be asked to decide on much more than who [...]