Spatial analysis identified Tregs as a source of local T cell repression, mediating resistance to KRAS-G12C-i and anti–PD-1.
High mtDNA levels increase tumor burden in mice through enhanced mitochondrial respiratory chain capacity.
The incorporation of pyramid-based asymmetrical optical transmission array boosts the efficiency of bifacial organic solar cells.
PSIP1 can act as a tumor suppressor gene during tumor initiation or as a dependency factor in tumor maintenance in T-ALL.
Engineering nanomedicines augment cancer immunotherapy through reprogramming cellular senescence of tumor microenvironment.
The innate immune system shapes brain development and is implicated in neurodevelopmental diseases. It is critical to define the relevant immune cells and signals and their impact on brain circuits. In this work, we found that group 2 innate lymphoid ...
Plants are frequently challenged by osmotic stresses. How plant cells sense environmental osmolarity changes is not fully understood. We report that Arabidopsis Decapping 5 (DCP5) functions as a multifunctional cytoplasmic osmosensor that senses and ...
Parrots produce stunning plumage colors through unique pigments called psittacofulvins. However, the mechanism underlying their ability to generate a spectrum of vibrant yellows, reds, and greens remains enigmatic. We uncover a unifying chemical basis ...
The π-bonds in unsaturated organic molecules are typically associated with having well-defined geometries that are conserved across diverse structural contexts. Nonetheless, these geometries can be distorted, leading to heightened reactivity of the π-...
The AlphaFold Protein Structure Database (AFDB) contains more than 214 million predicted protein structures composed of domains, which are independently folding units found in multiple structural and functional contexts. Identifying domains can enable ...
A poor labor report would typically send mortgage rates lower, but they're higher anyway. Here's what to know.
Here's how we see the NHL landscape as November begins.
Arvind Sawant, a Shiv Sena MP referred to Shaina NC as 'imported maal' on October 29, sparking outrage on social media.
Smaller countries should defend their interests and their vision more vigorously, Ambassador Extraordinary and Plenipotentiary of Cuba to Belarus Santiago Perez Benitez told the media on the margins of the 2nd Minsk International Conference on Eurasian Security on 1 November.
Insurers list North Memorial, HealthPartners as in-network next year, but health system owners say that’s wrong -- there’s no network contract yet.
Plus, spooky season is forever with new looks at Heretic, and more!
The superstar entertainer was addressing a speaker at Trump's Sunday rally who called Puerto Rico a 'floating island of garbage'
Rising home prices and rental rates are pushing many residents at the brink as the two presidential campaigns offer starkly contrasting visions for the economy.
Center focuses on interactivity, allows users to visualize the technology's impact on their lives
Macy’s Thanksgiving Day Parade is celebrating its 98th edition this year — that’s just two away from the big one! Before you gobble up your turkey dinner on Thanksgiving, gather your loved ones (and your pets) around the television to see your favorite celebrities and floats maneuver their way through the heart of New York […]
For a one-term president, the incumbent has a substantial record — which could easily be unwound
With a bit of soapy dialogue, dark humor, luxury, and a thrilling mystery at its heart, The Perfect Couple evokes these 10 novels.
US job growth slowed significantly in October due to hurricanes and labor strikes. Only 12,000 jobs were added, much lower than expected. Despite this, the unemployment rate remained at 4.1 percent. Both presidential candidates will scrutinize the data, with concerns about economic conditions and the impact on voters.
Is “Conclave” a Best Picture sleeper? Will “Emilia Pérez” endure backlash? Gold Derby editors and experts Christopher Rosen and Joyce Eng are here to answer your burning questions of the week. “Conclave” has been a modest hit since opening in theaters last weekend. The gossipy papal drama has been sitting in third place in the Best Picture Oscar […]
In September 2024, we reported that data experts Tim Vetter and Phani Mantravadi of Check My Vote identified 6,126 duplicate votes on the August primary voter rolls.
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