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Новости за 18.10.2024

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Sintilimab plus chemotherapy with or without bevacizumab biosimilar IBI305 in EGFR-mutated non-squamous NSCLC patients who progressed on EGFR TKI therapy: A China-based cost-effectiveness analysis

Plos.org 
En

by Juan Peng, Huiling Xu, Qiao Liu

Background

This study aims to compare the cost-effectiveness of sintilimab in combination with chemotherapy, with or without bevacizumab biosimilar IBI305, versus chemotherapy alone for patients with epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) who have progressed on tyrosine-kinase inhibitor (TKI) treatment from the perspective of the Chinese healthcare system.

Methods

10-year Markov model was developed using a 21-day cycle length. Читать дальше...

We need to aim at the top: Factors associated with cybersecurity awareness of cyber and information security decision-makers

Plos.org 
En

by Simon Vrhovec, Blaž Markelj

Cyberattacks pose a significant business risk to organizations. Although there is ample literature focusing on why people pose a major risk to organizational cybersecurity and how to deal with it, there is surprisingly little we know about cyber and information security decision-makers who are essentially the people in charge of setting up and maintaining organizational cybersecurity. In this paper, we study cybersecurity awareness of cyber and information security decision-makers... Читать дальше...

The impact of emotion regulation on the establishment of the therapeutic alliance in post-divorce group intervention: A multilevel approach

Plos.org 
En

by Irati Alvarez, Marta Herrero, Ana Martínez-Pampliega

Objective

The present study focuses on the impact of emotion regulation on the establishment of the therapeutic alliance in a context of post-divorce group intervention.

Method

The study involved 177 divorced parents and 60 therapists and was developed through multilevel path analysis.

Results

The data showed an association between emotion regulation and therapeutic alliance across the difficulties of adaptation to divorce... Читать дальше...

Intraspecific venom variation in the medically important puff adder (Bitis arietans): Comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom

Plos.org 
En

by Charlotte A. Dawson, Keirah E. Bartlett, Mark C. Wilkinson, Stuart Ainsworth, Laura-Oana Albulescu, Taline Kazandijan, Steven R. Hall, Adam Westhorpe, Rachel Clare, Simon Wagstaff, Cassandra M. Modahl, Robert A. Harrison, Nicholas R. Casewell

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Introducing Atlantic Labs: Research and Experiments from The Atlantic’s Product Team

The Atlantic  
En

Today The Atlantic is launching Atlantic Labs, a research and development site from the product and technology team. The product team will use this space to incubate ideas, many using AI, to understand how The Atlantic can benefit from emerging technologies. This is a destination for works in progress and prototypes, and to test––and learn from––new technologies.

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