ru24.pro
News in English
Октябрь
2024

Новости за 15.10.2024

Community-Acquired Pneumonia: A Review

Jamanetwork.com 

This Review summarizes current evidence on pathogenesis, epidemiology, diagnosis, and treatment of community-acquired pneumonia and focuses on adults without immune-compromising conditions.

Error in Discussion Section

Jamanetwork.com 

The Review titled “Management of Depression in Adults: A Review,” published on June 10, 2024, was corrected to add missing absolute difference data in the Selection of First-Line Treatment subsection of the Discussion. This article was corrected online.

Prescription Drug Patent Reform

Jamanetwork.com 

This Viewpoint summarizes the role of the Patent Trial and Appeal Board (PTAB) in reforming the drug patent process to avoid erroneously granted patents; highlights how other reform efforts, such as the PREVAIL Act, actually weaken the PTAB; and suggests changes to strengthen the PTAB and promote generic availability and reduced health care costs.

Interchangeability of Biosimilars

Jamanetwork.com 

This Viewpoint from the US Food and Drug Administration (FDA) summarizes a recent update to an FDA draft interchangeability guidance regarding the need for clinical switching studies to illustrate the FDA’s ongoing efforts to streamline the development of biosimilar medications that are in line with the latest science.

Sonnet at the Supermarket

Jamanetwork.com 

His eyes wash over families of fruit, crushed cardboard, sticky hands. The trick is to be molecular: a watermelon sick with jaundice is no good, mushy inside. Carries disease internal to itself. Like how cells hold instructions for their own death or how birds always know the way home. His eyes washed with chemical droplets and still unseeing. Like light flushed down the sink. Shade of white so brutal it could kill you. Choose the roundest, brightest fruit, says Appa. Glaucoma, from glausso, from glow... Читать дальше...

Prognostic Value of Cardiovascular Biomarkers—Reply

Jamanetwork.com 

In Reply We recently reported that cardiovascular biomarkers were strongly associated with fatal and nonfatal cardiovascular events and mortality, but their addition to established risk factors resulted in only a small improvement in risk prediction metrics.

Prognostic Value of Cardiovascular Biomarkers

Jamanetwork.com 

To the Editor A recent study that aimed to assess the prognostic value of routinely available cardiovascular biomarkers when added to established risk factors found that incorporating these biomarkers resulted in only a modest improvement in risk prediction metrics for atherosclerotic cardiovascular disease. However, the improvement was more notable for predicting heart failure and mortality. Despite these interesting results, several issues warrant further attention.

Word Choice and the Patient Encounter

Jamanetwork.com 

This JAMA Insights in the Communicating Medicine series explores how differences in word choice can affect both visit interactions and visit outcomes in patient encounters.

Speed Limits

Jamanetwork.com 

In this narrative medicine essay, a pediatrician discusses the ambiguity of diagnoses of patients and settles on honestly admitting when the parameters are unclear with an explanation of the range of possibilities.

Patient Information: What Is Lupus?

Jamanetwork.com 

This JAMA Patient Page describes the autoimmune disease systemic lupus erythematosus and its symptoms, diagnosis, treatment, and prognosis.

Be Your Own Philosopher

Jamanetwork.com 

Contrary to prevailing impression, medicine’s concern with ethical problems is not a by-product of recent advances in medical knowledge and skills. True, problems such as allotment of a limited organ supply among the many in need of a transplant or deciding to terminate an artificially sustained life did not exist in the past, but abortion, euthanasia, and other issues have always presented dilemmas. Some of these, such as the decision to save the life of a mother or the newborn, were even more frequent than they are now... Читать дальше...

Errors in Table 1

Jamanetwork.com 

The Review titled “Perioperative Management of Patients Taking Direct Oral Anticoagulants: A Review,” published on August 12, 2024, was corrected to fix several typographical errors in the last column of Table 1. This article was corrected online.

Risk Factors for Immune Checkpoint Inhibitor-Induced Diabetes Identified

Jamanetwork.com 

Immunotherapy drugs known as immune checkpoint inhibitors have improved long-term cancer survival rates by allowing a person’s immune system to attack tumor cells. But there has been concern about their role in inflammatory and autoimmune disorders, known as immune-related adverse events, that can include hypothyroidism, colitis, and diabetes.

Hormone Therapy Associated With Slower Biological Aging in Menopause

Jamanetwork.com 

Postmenopausal people who used hormone therapy (HT) displayed fewer signs of biological aging, according to an observational study published in JAMA Network Open. The researchers used data based on about 118 000 postmenopausal women with an average age of 60 years in the UK Biobank.

Study: Heat-Related Deaths on the Rise in US Since 2016

Jamanetwork.com 

The number of heat-related deaths in the US has more than doubled in the past quarter century, increasing from roughly 1100 in 1999 to more than 2300 in 2023, a study in JAMA Network Open found. Heat-related mortality rates have been rising steadily since 2016, the researchers noted, with the highest number recorded in 2023, the hottest year on record.

Action Needed to Ease Parental Stress, US Surgeon General Warns

Jamanetwork.com 

US Surgeon General Vivek Murthy, MD, MBA, issued an advisory on the mental health and well-being of parents and caregivers of children younger than 18 years. The report comes in response to the intense pressure reported by the roughly 63 million parents of children in the US: 33% reported high levels of stress over the course of a month compared with 20% of other adults in 2023.

FDA Approves First Automated Insulin Device for Type 2 Diabetes

Jamanetwork.com 

The US Food and Drug Administration (FDA) expanded approval of an automated insulin delivery system to include its use for people with type 2 diabetes aged 18 years or older. The software, marketed as the Insulet SmartAdjust, works with an automated insulin pump and a glucose sensor to adjust insulin delivery every 5 minutes. The FDA previously authorized it for those with type 1 diabetes aged 2 years or older.