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Новости за 14.10.2024

Human motor learning dynamics in high-dimensional tasks

Plos.org 

by Ankur Kamboj, Rajiv Ranganathan, Xiaobo Tan, Vaibhav Srivastava

Conventional approaches to enhance movement coordination, such as providing instructions and visual feedback, are often inadequate in complex motor tasks with multiple degrees of freedom (DoFs). To effectively address coordination deficits in such complex motor systems, it becomes imperative to develop interventions grounded in a model of human motor learning; however, modeling such learning processes is challenging due to the large DoFs. Читать дальше...

Emergent order in epithelial sheets by interplay of cell divisions and cell fate regulation

Plos.org 

by Philip Greulich

The fate choices of stem cells between self-renewal and differentiation are often tightly regulated by juxtacrine (cell-cell contact) signalling. Here, we assess how the interplay between cell division, cell fate choices, and juxtacrine signalling can affect the macroscopic ordering of cell types in self-renewing epithelial sheets, by studying a simple spatial cell fate model with cells being arranged on a 2D lattice. We show in this model that if cells commit to their fate directly upon cell division... Читать дальше...

Reduction of endocytosis and EGFR signaling is associated with the switch from isolated to clustered apoptosis during epithelial tissue remodeling in Drosophila

Plos.org 

by Kevin Yuswan, Xiaofei Sun, Erina Kuranaga, Daiki Umetsu

Epithelial tissues undergo cell turnover both during development and for homeostatic maintenance. Removal of cells is coordinated with the increase in number of newly dividing cells to maintain barrier function of the tissue. In Drosophila metamorphosis, larval epidermal cells (LECs) are replaced by adult precursor cells called histoblasts. Removal of LECs must counterbalance the exponentially increasing adult histoblasts. Previous... Читать дальше...

7 Expert Strategies to Beat Every Google SEO Update and Boost Your Search Power

Entrepreneur.com 

In a landscape where Google's updates can rapidly shift search rankings, staying visible requires more than basic SEO tactics. Here are seven advanced strategies, from structuring content around topic clusters to optimizing for zero-click searches, all designed to help you maintain and boost your search visibility as you head into 2025.

Council defends £35k corgi statues

Express & Star 

Walsall Council has defended its decision to commission two corgi statues costing £35,000 of taxpayers money - even though some said the money 'could have been spent elsewhere'.