p63 blocks the squamous-to-neuroendocrine transition, whereas EZH2 represses p63 in esophageal neuroendocrine carcinoma.
Early humans diversified their food availability by adapting to rugged terrain, leading to niche expansion.
A one-carbon ring expansion reaction of N-heterocycles enables divergent asymmetric catalysis.
Photonic textiles offer smart temperature control, ensuring comfort in a sustainable future.
VGLL3 has an unexpected function in promoting DNA repair through stabilizing CtIP and MDC1 proteins.
Sparse dynamic nanotomography method provides 40-time speed increase and sub–30 nm resolution for in situ hydration of PEFC.
Structure of a unique RC-LH1 dimer spotlights the structural and functional variability of bacterial photosynthetic systems.
The levels of LINE1 expression regulate the rate of protein synthesis throughout the human life span.
Cryo-EM structures reveal how human acetyl-CoA carboxylase 1 changes shape to control its activity.
3D data of the heads of Arthropleura show that it shares trunk affinities with millipedes and head affinities with centipedes.
Defect-tolerant compound semiconductors deposited from solution enable high-speed logic circuits and high-resolution displays.
Large Arctic catchment sulfide oxidation and CO2 release increased by 45%, representing positive feedback on warming.
A gene therapy toolbox allows noninvasive magnetic field regulation of targeted neural circuit activity in vivo.
Mutations that perturb interaction between CED-9 and CED-4 disrupt the pro-apoptotic but not the anti-apoptotic function of CED-9.
Joshua Stutts talks about his club and family and shares his favorite thing he owns.
Читать дальше...The GOP will be an unmanageable mess if he loses, which means the party may go far to help him deny defeat.
The director of ‘The Queen of Versailles’ watched 2,000 hours of teens’ screen time. What she saw shocked her.
Folie à Deux never shows us this TV movie, perhaps because that would be funny and interesting, two qualities the film abhors. But it got me thinking.
Next up: a Jonathan Groff–starring Bobby Darin bio-musical, Just in Time, with a big band.
A dual-layered protection system, the solution has two filters - one at the network layer and the second at the IT systems layer
The Audacious Project supports big ideas to foster change around the world’s most urgent challenges. Today, this innovative funding initiative, housed at TED, is announcing its new cohort of projects for 2024, which are as bold as ever — from an idea to repurpose generic drugs en masse to reach the 300 million people globally […]
When Beyonce is eligible at the Grammys, you can typically expect her to be one of the most nominated artists of the year. She picked up 10 bids in 2010, and she was up for nine awards in 2017, 2021, and 2023. Altogether she’s tied with her husband Jay-Z for the most Grammy nominations ever […]
For fans of Wright's style, there are homes to be had by his proteges. They range in price points in various parts of the country.
CRCA’s executive director says the TFW program is needed to help CRCA members fill existing gaps.
Ruben Gallego and Kari Lake are preparing to meet for the only debate of the Arizona Senate race. Their matchup on Wednesday comes as voters begin casting ballots in a contest that will help determine control of the U.S. Senate. Lake is a well-known former television news anchor and a darling of the populist right. She has tried but struggled to redefine herself since losing the 2022 race for governor. Gallego is a Democratic congressman representing largely Latino areas of Phoenix. He's used his... Читать дальше...