by Monica Dwi Hartanti, Novaria Sari Dewi Panjaitan, Sunarno Sunarno, Nathalia Ningrum, Armedy Ronny Hasugian, Rita Marleta Dewi, Sarwo Handayani, Masri Sembiring Maha, Firda Fairuza, Meiriani Sari, Dita Setiati, Christina Safira Whinie Lestari
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by Davide Dal Pos, Barbara J. Sharanowski
The evolution of convergent phenotypes is of major interest in biology because of their omnipresence and ability to inform the study of evolutionary novelty and constraint. Convergent phenotypes can be combinations of traits that evolve concertedly, called syndromes, and these can be shaped by a common environmental pressure. Parasitoid wasps which use a wide variety of arthropod hosts have also repeatedly and convergently switched host use across their evolutionary history. Читать дальше...
by Nicky de Vrij, Romi Vandoren, Kadrie Ramadan, Anke Van Hul, Ann Ceulemans, Mekibib Kassa, Roma Melkamu, Arega Yeshanew, Tadfe Bogale, Hailemariam Beyene, Kasaye Sisay, Aderajew Kibret, Dagnew Mersha, Wim L. Cuypers, Florian Vogt, Saskia van Henten, Koert Ritmeijer, Thao-Thy Pham, Pieter Meysman, Kris Laukens, Bart Cuypers, Ermias Diro, Rezika Mohammed, Johan van Griensven, Wim Adriaensen
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by Nancy Cure-Bolt, Fernando Perez, Lindsay A. Broadfield, Bruno Levecke, Peter Hu, John Oleynick, María Beltrán, Peter Ward, Lieven Stuyver
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by Ho Yin Pekkle Lam, Yu-Ting Huang, Ting-Ruei Liang, Shih-Yi Peng
Human angiostrongyliasis, caused by consuming the larva stage of Angiostrongylus cantonensis, is an infectious disease involving the central nervous system (CNS) and ophthalmic system. Current treatment of angiostrongyliasis involves albendazole accompanied by analgesics and corticosteroids. However, long-term use of corticosteroids may lead to significant adverse effects. In the current study, we screened through different... Читать дальше...
by Didot Budi Prasetyo, Jodi M. Fiorenzano, Daliya Nop, Nin Noch, Boren Huot, Sokly Mom, Sitha Prum, Visal Chhe, Sokha Dul, Vireak Heang, Satharath Prom, Ju Jiang, Allen L. Richards, Christina M. Farris, Jeffrey C. Hertz
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by Moe Ikegawa, Norisuke Kano, Daisuke Ori, Mizuki Fukuta, Minato Hirano, Roger Hewson, Kentaro Yoshii, Taro Kawai, Takumi Kawasaki
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by Hanmin Guo, Alexander Eckehart Urban, Wing Hung Wong
Rare variants, comprising the vast majority of human genetic variations, are likely to have more deleterious impact in the context of human diseases compared to common variants. Here we present carrier statistic, a statistical framework to prioritize disease-related rare variants by integrating gene expression data. By quantifying the impact of rare variants on gene expression, carrier statistic can prioritize those rare variants that... Читать дальше...
by Margherita Molaro, Sakshi Mohan, Bingling She, Martin Chalkley, Tim Colbourn, Joseph H. Collins, Emilia Connolly, Matthew M. Graham, Eva Janoušková, Ines Li Lin, Gerald Manthalu, Emmanuel Mnjowe, Dominic Nkhoma, Pakwanja D. Twea, Andrew N. Phillips, Paul Revill, Asif U. Tamuri, Joseph Mfutso-Bengo, Tara D. Mangal, Timothy B. Hallett
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by Yutaro Kumagai
Recent advances in measurement technologies, particularly single-cell RNA sequencing (scRNA-seq), have revolutionized our ability to acquire large amounts of omics-level data on cellular states. As measurement techniques evolve, there has been an increasing need for data analysis methodologies, especially those focused on cell-type identification and inference of gene regulatory networks (GRNs). We have developed a new method named BootCellNet, which employs smoothing and resampling to infer GRNs. Читать дальше...
by Helder V. Ribeiro-Filho, Gabriel E. Jara, João V. S. Guerra, Melyssa Cheung, Nathaniel R. Felbinger, José G. C. Pereira, Brian G. Pierce, Paulo S. Lopes-de-Oliveira
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by Kevin Tsai, Zhen Zhou, Jiadong Yang, Zhiliang Xu, Shixin Xu, Roya Zandi, Nan Hao, Weitao Chen, Mark Alber
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by Biao Tang, Kexin Ma, Yan Liu, Xia Wang, Sanyi Tang, Yanni Xiao, Robert A. Cheke
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by Ron Zeira, Leon Anavy, Zohar Yakhini, Ehud Rivlin, Daniel Freedman
Solid tumors are characterized by complex interactions between the tumor, the immune system and the microenvironment. These interactions and intra-tumor variations have both diagnostic and prognostic significance and implications. However, quantifying the underlying processes in patient samples requires expensive and complicated molecular experiments. In contrast, H&E staining is typically performed as part of the routine standard process, and is very cheap. Читать дальше...
by Jacob A. Mayfield, Sahadevan Raman, Alexandrea K. Ramnarine, Vivek K. Mishra, Annie D. Huang, Sandrine Dudoit, Jeffrey Buter, Tan-Yun Cheng, David C. Young, Yashodhan M. Nair, Isobel G. Ouellet, Braden T. Griebel, Shuyi Ma, David R. Sherman, Ludovic Mallet, Kyu Y. Rhee, Adriaan J. Minnaard, D. Branch Moody
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Discover this essential checklist for evaluating your business after its first year of operation, covering financial health, market position and operational efficiency to help you assess performance and plan for future growth.
Activity goals are supposed to be for humans, not machines.
A porcupine fossil recovered in Florida was the key clue in solving a paleontological mystery.
While the club and the players may not see it this way, Dominic Solanke has taken up the unenviable mantle left behind by Harry Kane... The post Solanke reveals what Harry Kane told him in private chat after joining Spurs appeared first on Spurs Web.
The Boston Red Sox finished their 2024 season with an 81-81 record, good for third place in the American League East but not enough for a postseason berth. The Red Sox have several talented young players and they sparked a hot stretch over the summer that had Boston 11 games over .500 at the All-Star […]
The police chased a woman who was driving dangerously, and found drugs in her possession.
The Ministry of Tourism successfully showcased Bulgaria at Tourism Expo Japan 2024, attracting significant attention and drawing hundreds of visitors interested in exploring tourism opportunities in the country. Bulgaria's stand, occupying 72 square meters at the Tokyo exhibition, was presented in collaboration with the Municipality of Kazanlak, the Municipality of Plovdiv, the Capital Municipality, Bohemia Ltd., and Tandem Travel Ltd....
Three men who allegedly attempted to rob a jewellery store in Queensland have been thwarted by a pair of barbers.
With the 2024 US presidential election roughly one month away, one could be forgiven for thinking that Republican nominee Donald Trump would be too preoccupied to venture into a new retail market.
A man who was involved in an alleged plot to fake a luxury jewellery store robbery in Sydney has been jailed.