Morphological multiparameter filtration and persistent homology in mitochondrial image analysis
by Yu-Min Chung, Chuan-Shen Hu, Emily Sun, Henry C. Tseng
The complexity of branching and curvilinear morphology of a complete mitochondrial network within each cell is challenging to analyze and quantify. To address this challenge, we developed an image analysis technique using persistent homology with a multiparameter filtration framework, combining image processing techniques in mathematical morphology. We show that such filtrations contain both topological and geometric information about complex cellular organelle structures... Читать дальше...