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Новости за 12.09.2024

Calibrating dimension reduction hyperparameters in the presence of noise

Plos.org 

by Justin Lin, Julia Fukuyama

The goal of dimension reduction tools is to construct a low-dimensional representation of high-dimensional data. These tools are employed for a variety of reasons such as noise reduction, visualization, and to lower computational costs. However, there is a fundamental issue that is discussed in other modeling problems that is often overlooked in dimension reduction—overfitting. In the context of other modeling problems, techniques such as feature-selection, cross-validation... Читать дальше...

Comparison and benchmark of deep learning methods for non-coding RNA classification

Plos.org 

by Constance Creux, Farida Zehraoui, François Radvanyi, Fariza Tahi

The involvement of non-coding RNAs in biological processes and diseases has made the exploration of their functions crucial. Most non-coding RNAs have yet to be studied, creating the need for methods that can rapidly classify large sets of non-coding RNAs into functional groups, or classes. In recent years, the success of deep learning in various domains led to its application to non-coding RNA classification. Multiple novel architectures have been developed... Читать дальше...

Remember oligodendrocytes: Uncovering their overlooked role in Alzheimer’s disease

Plos.org 

by Lena Spieth, Mikael Simons

Our understanding of Alzheimer’s disease (AD) has evolved from focusing solely on neurons to recognizing the role of glia. A recent study in PLOS Biology revealed that oligodendrocytes are an important source of Aβ that impairs neuronal function. Our understanding of Alzheimer’s disease has evolved from focusing solely on neurons to recognizing the role of glia. This Primer discusses a recent study in PLOS Biology that showed that oligodendrocytes are an important... Читать дальше...

Mariners Moose Tracks, 9/12/24: James Paxton, Shohei Ohtani, and Porter Hodge

Lookout Landing 

Troy Taormina-USA TODAY Sports

We’ll miss you, Pax.

Good morning friends! Let’s check in on the latest news from the baseball world.

In Mariners news...

  • In his latest radio spot for 710 ESPN Seattle, Jeff Passan pitched the Red Sox as potential offseason trade partners for the Mariners.

Around the league...

  • In some bittersweet news, our beloved James Paxton announced that he is retiring from baseball at the end of the season.
  • Shohei Ohtani 50/50 Watch update... Читать дальше...

Elephant Rumblings: Looking for the sweep

Athletics Nation 

Troy Taormina-Imagn Images

MLB news roundup

Good morning Athletics Nation!

The Athletics stole the first two games from the division rival Houston Astros. Things are going well. We have secured the series win. The club will now have a chance at a three-game sweep, which would be their first since early July. Playing spoiler is always fun but doing it against these guys is extra juicy. Houston is still currently in position to go to the playoffs yet again but they’re not looking... Читать дальше...

To Make My Old Ass, Megan Park Had to Confront a Teenage Dream

VanityFair.com 

Park moved beyond acting roles in The Secret Life of the American Teenager and the Hallmark universe to experience her own coming of age: “I get so much joy from writing and directing that I never really felt being in front of the camera.”

Report: Bissouma makes smart decision to maximise chances of NLD return

TheSpursWeb 

Yves Bissouma picked up an injury on international duty this week, but he has done everything he can in order to get back to full... The post Report: Bissouma makes smart decision to maximise chances of NLD return appeared first on The Spurs Web - Tottenham Hotspur Football News.

Thursday Night Football: How to Watch the Bills/Dolphins Game Live Online

TVLine.com 

Don’t be fooled by NFL’s kick-off last Thursday via NBC’s Sunday Night Football. Here’s how to watch the Buffalo Bills vs. Miami Dolphins in the first Thursday Night Football game, plus get every matchup and game time of the 2024 NFL season. Thursday Night Football: How to Watch Bills vs. Dolphins Online The NFL began […]