This cross-sectional study uses data from the 2022 Tobacco Use Supplement of the Current Population Survey to estimate the prevalence of adult US nicotine pouch use and the characteristics of the individuals using pouches.
This Viewpoint discusses the high cost of new gene therapies for sickle cell disease, the challenges these costs pose for health care access, and new policy approaches to ensure fair reimbursement for payers and manufacturers without further increasing health care costs or barriers to access for underserved populations.
This Review summarizes the current evidence regarding the epidemiology, pathophysiology, diagnosis, and treatment of obesity in adolescents, with a focus on management of obesity.
She yelled at me this morning when I walked to the kitchen with my dirty laundry and put it in the trash can.
In Reply We appreciate the letter to the editor by Dr Tu and colleagues regarding our recent analysis of 2 randomized trials to derive and externally validate individualized treatment effects of lower vs higher oxygen-saturation (Spo2) targets on mortality in mechanically ventilated critically ill adults. The authors raise 3 points, which we address here.
To the Editor A recent study by Dr Buell and colleagues addresses an important aspect of care in the intensive care unit (ICU), individualized oxygenation targets for mechanically ventilated critically ill adults. Although the study contributes valuable insights into the nuanced nature of oxygen therapy, there are several areas where the methodology and interpretation of results could be enhanced to strengthen the conclusions drawn.
This JAMA Patient Page describes e-cigarettes and the potential health effects of vaping.
This randomized clinical trial compares the effectiveness of a tailored, interactive text message program for nicotine vaping cessation vs assessment only among US adolescents aged 13-17 years.
This study characterizes and quantifies constituents in 2 e-cigarette products to assess product consistency and inform future risk assessments.
Mankind has traditionally included in the daily regimen a variety of substances that do not function as true nutrients. Some of them are so unlike the natural foods that they can scarcely be regarded as adventitious contaminants of the ration. Certain beverages, such as coffee, tea and cocoa, are concocted in an admittedly artificial manner.…Similarly, fermented beverages and distilled liquors have a common potent constituent, alcohol, that can function as a drug as well as a food. Under certain... Читать дальше...
This JAMA Insights explores the adverse effects and health outcomes of e-cigarettes vs combusted cigarettes and the effectiveness of using e-cigarettes as a smoking cessation aid among US adults.
Electronic cigarettes (e-cigarettes) are the most widely used tobacco/nicotine product among US middle and high school adolescents. According to data from the 2023 National Youth Tobacco Survey, 2 million US middle and high school students (approximately 7%) reported using an e-cigarette in the past 30 days, including 10% of all US high school students (more than 1.5 million adolescents) and 4.6% of all US middle school students (550 000 adolescents).
This Viewpoint summarizes methods used by health care organizations to assess and improve clinician well-being, discusses the potential downsides of public reporting of clinician well-being survey data, and calls for making organizations’ adherence to structure and process measures a part of accreditation criteria.
In this narrative medicine essay, a pediatric and internal medicine physician and her husband reach a difficult crossroads upon learning that their unborn daughter has a severe heart defect.
This population-based case-control study assesses the association of commonly prescribed oral antibiotics with serious cutaneous adverse drug reactions and characterizes outcomes of patients hospitalized for them.
In Reply The Letter to the Editor from Dr Watkins and colleagues about our Review on SLE raises the important topic of congenital heart block risk for the infants of pregnant individuals with SLE and anti-Ro/SSA antibody positivity. Although our article mentioned the association between anti-Ro/SSA antibody and neonatal lupus erythematosus, an acquired inflammatory syndrome that may include congenital heart block, further discussion was beyond the scope of our Review.
In Reply Drs Xia and Su raise several queries about our study, the aMAZE trial. First, they state, “The study did not assess left atrial appendage electrical isolation, which is important considering the mechanism of action of the intervention,” implying this affected outcomes. The proposed mechanism of action of LAA ligation as adjunctive therapy to PVI was 2-fold: LAA electrical isolation and left atrial volume (LAV) reduction. LAA ligation results in LAA ischemic necrosis, atrophy, and resorption, analogous to amputation. Читать дальше...
To the Editor A recent Review provided comprehensive information about the manifestations and treatment options for patients with systemic lupus erythematous (SLE). As maternal-fetal medicine subspecialists, we hope to provide additional insight into an obstetrical complication that can arise in patients with SLE during pregnancy and discuss current management recommendations.
To the Editor A recent study investigated the safety and effectiveness of percutaneous left atrial appendage (LAA) ligation with catheter pulmonary vein isolation (PVI) for nonparoxysmal atrial fibrillation (AF). Although the study design and execution were commendable, we have several concerns about its methodology and interpretation. First, the study’s primary outcome measure of freedom from documented atrial arrhythmias at 12 months may not have fully captured the efficacy of percutaneous LAA ligation adjunctive to PVI isolation. Читать дальше...
This Medical News story examines the controversy surrounding the FDA’s first authorization of flavored e-cigarettes, in this case menthol.
This JAMA Insights reviews the health effects of vaping among youth in the US and current recommendations for screening and treatment.
The introduction of electronic cigarettes (e-cigarettes) in recent years has created new dilemmas for clinical and research communities. E-cigarettes are battery-powered devices that heat liquids containing nicotine, flavoring, and other substances to create aerosols. Their use is often called “vaping.” E-cigarettes have been marketed as safer alternatives to cigarettes because they do not contain the carcinogens found in combustible tobacco products. More than 4.5% of US adults, 10% of high school students... Читать дальше...
This Medical News article is an interview with US Surgeon General Vivek Murthy, MD, MBA, and JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, about his call for a warning label on social media platforms.
Children absorb much less nicotine from secondhand e-cigarette vapor than from secondhand tobacco smoke, according to a study of roughly 1800 children in the US aged 3 to 11 years.
The Mediterranean diet, which emphasizes eating more fruits, vegetables, legumes, and healthy fats, has already been associated with health benefits for adults. Now, a systematic review suggests it may have similar effects on children and teens. Researchers analyzed data from 9 randomized clinical trials involving 577 children aged 3 years to 18 years that measured the effects of Mediterranean diet–based interventions on cardiometabolic markers.