A structural and genomic analysis of the DNMT3A1 interaction with H2AK119Ub nucleosomes explains its mistargeting in cancer.
Cytokinin is confined to the single pluripotent stem cell and excludes ALOG proteins, the differentiation factor, in bryophytes.
Choreographed from physics equations, a dance features people collectively behaving as a topological insulator.
Natural killer cell reactivity decreases rapidly upon activation by tumor cells, independently of immune checkpoints.
Microglia in embryonic zebrafish brain are pu.1 dependent and lymphatic independent.
TaWAK2-A is involved in the regulation of cytokinin signaling and contributes to leaf development in wheat.
CYP706C2 is essential for biosynthesis of a noncanonical rice strigolactone that is involved in symbiosis and root development.
A microfluidics-assembled thermosensitive foam nanoengine improves insulin-pramlintide delivery for efficient glycemic control.
Pharmacological degradation of ENL induced by degrader molecules is a promising treatment strategy for ENL-dependent cancers.
Adoptive cell therapy is enhanced by treatment of T cells with a HIF stabilizer and costimulatory receptor agonist antibodies.
Developmental DNA demethylation confers identity and gliogenic competence to neural stem cells by commissioning enhancers.
Algorithm to design intrinsically disordered proteins with specific conformational properties expands the protein design toolbox.
Double-functionalized STM tips with superconducting cluster and CO molecule reveal unique superconducting interference patterns.
Fluoroamphiphilic polymers exhibit selective antimicrobial ability toward multidrug-resistant Gram-negative ESKAPE bacteria.
Medieval genomes unveil genetic continuity, infections, and family relationships within an isolated population in Northern Iberia.
Millimeter-scale capsules enable sampling liquids in fluid-filled confined spaces for targeted liquid biopsy in disease diagnosis.
A pneumatic OCT endoscope allows for navigational and distortion-free imaging in tortuous and narrow luminal organs.
Transient gene perturbations cause heritable transcriptomic changes in E. coli, thus one genotype can have multiple phenotypes.
Humans and chimpanzees show brain aging, while its spatial distribution relates to evolutionary expansion only in humans.
Because of a production error in the Research Article “MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells” by S. Perrin et al., the references cited in the Supplementary Materials were missing from the published article. These references have been added to the References and Notes list as numbers 57 to 68 in the PDF and the HTML, and the Supplementary Materials PDF has been updated with these reference numbers. The data and conclusions are not affected.
Virat Kohli moved to eighth in the ICC Test rankings, while Rohit Sharma dropped to sixth, scroll down for the latest Test ICC rankings.
Israeli forces carried out a series of attacks on the West Bank overnight, killing at least nine people and forcing more Palestinians to evacuate their homes. It comes a day after a hostage was rescued from Gaza.
SBI has experienced remarkable growth in its net interest income, surging by an impressive 60% in just four years. It rose from under Rs 1 lakh crore in FY20 to Rs 1.60 lakh crore in FY24.
I flew to Berlin on the Prime Minister's plane - and it was very comfortable, but not quite Beyoncé. Here's a behind the scenes look at what it's like to fly Keir Starm-Air
We get Eve and Nick’s relationship from love at first sight to double insurance fraud and multiple murder sprees.