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Новости за 08.08.2024

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scRNMF: An imputation method for single-cell RNA-seq data by robust and non-negative matrix factorization

Plos.org 
En

by Yuqing Qian, Quan Zou, Mengyuan Zhao, Yi Liu, Fei Guo, Yijie Ding

Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool in genomics research, enabling the analysis of gene expression at the individual cell level. However, scRNA-seq data often suffer from a high rate of dropouts, where certain genes fail to be detected in specific cells due to technical limitations. This missing data can introduce biases and hinder downstream analysis. To overcome this challenge, the development... Читать дальше...

Interacting particle models on the impact of spatially heterogeneous human behavioral factors on dynamics of infectious diseases

Plos.org 
En

by Yunfeng Xiong, Chuntian Wang, Yuan Zhang

Human behaviors have non-negligible impacts on spread of contagious disease. For instance, large-scale gathering and high mobility of population could lead to accelerated disease transmission, while public behavioral changes in response to pandemics may effectively reduce contacts and suppress the peak of the outbreak. In order to understand how spatial characteristics like population mobility and clustering interplay with epidemic outbreaks, we... Читать дальше...

Convolutional neural networks can identify brain interactions involved in decoding spatial auditory attention

Plos.org 
En

by Keyvan Mahjoory, Andreas Bahmer, Molly J. Henry

Human listeners have the ability to direct their attention to a single speaker in a multi-talker environment. The neural correlates of selective attention can be decoded from a single trial of electroencephalography (EEG) data. In this study, leveraging the source-reconstructed and anatomically-resolved EEG data as inputs, we sought to employ CNN as an interpretable model to uncover task-specific interactions between brain regions, rather... Читать дальше...

Diatom abundance in the polar oceans is predicted by genome size

Plos.org 
En

by Wade R. Roberts, Adam M. Siepielski, Andrew J. Alverson

A principal goal in ecology is to identify the determinants of species abundances in nature. Body size has emerged as a fundamental and repeatable predictor of abundance, with smaller organisms occurring in greater numbers than larger ones. A biogeographic component, known as Bergmann’s rule, describes the preponderance, across taxonomic groups, of larger-bodied organisms in colder areas. Although undeniably important, the extent... Читать дальше...

Hall of Fame controversies

Royals Review 
En

SetNumber: X57689 TK3 F19 R12

Big Hall or small Hall?

I recently went on a road trip across part of our great nation and noticed a proliferation of signs that said, “visit our historic downtown”. From small villages to medium sized cities, it seems every downtown is now a historic one. About ten years ago someone at a Chamber of Commerce convention must have done one hell of a sales job to convince every town that they have a historic downtown. What we really have is a misunderstanding of history. Читать дальше...

Matthew Boyd nearly perfect for Columbus, Chase DeLauter blasts three-run bomb in Akron win

Let's Go Tribe 
En

Cleveland Guardians minor league recap for Thursday, Aug. 8, 2024

Columbus Clippers 2, St. Paul Saints 4

Box Score · Clippers fall to 55-53

This was a brutal loss for the Clippers because they outhit St. Paul 10-5 and even outwalked St. Paul 5-2, yet somehow they lost 4-2 because St. Paul had all its hits and walks pretty much in the same inning, scoring four runs in the eighth.

On the bright side, on a day where Cleveland showed it desperately needed starting pitching help at the MLB level... Читать дальше...

These Are The Worst Cars Our Readers Have Ever Driven

Jalopnik.com 
En

Cars are fun, but complaining about cars is even more fun. Of course, the standard of what constitutes a bad car changes over time, and the worst new car on sale today is probably objectively better to drive than many of the best cars 50-plus years ago. Without putting any restrictions on how old the car was when you…

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