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Новости за 29.07.2024

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Anxiety and depression among hypertensive patients during the COVID-19 pandemic: A cross-sectional study from Kathmandu Metropolitan, Nepal

Plos.org 
En

by Dilasha K. C., Hari Prasad Kaphle, Durga Shrestha, Nirmala Neupane

Introduction

The outbreak of a global pandemic like COVID-19 has highlighted significant distress around mental health. The burden of mental health issues like anxiety and depression requires evidence-based intervention, especially in low-income settings like Nepal. The study aims to determine the prevalence of anxiety and depression and the factors associated with it among hypertensive patients.

Materials and methods... Читать дальше...

Association between various physical activity domains and overall cancer risk, National Health and Nutrition Examination Survey (NHANES) 2007–2018

Plos.org 
En

by Yanxue Lian, Pincheng Luo

Purpose

There are very few studies concurrently evaluating the association between multiple physical activity (PA) domains and cancer prevalence. Therefore, this study aims to fill this gap by investigating the link between multiple PA subdomains [occupational PA (OPA), transportation-related PA (TPA), leisure-time PA (LTPA), and total PA] and the likelihood of cancer.

Method

The data from National Health and Nutrition Examination Survey (NHANES) 2007–2008... Читать дальше...

Correction: Using whole-genome sequence data to examine the epidemiology of Salmonella, Escherichia coli and associated antimicrobial resistance in raccoons (Procyon lotor), swine manure pits, and soil samples on swine farms in southern Ontario, Canada

Plos.org 
En

by Nadine A. Vogt, Benjamin M. Hetman, David L. Pearl, Adam A. Vogt, Richard J. Reid-Smith, E. Jane Parmley, Nicol Janecko, Amrita Bharat, Michael R. Mulvey, Nicole Ricker, Kristin J. Bondo, Samantha E. Allen, Claire M. Jardine

Could prophylactic antivirals reduce dengue incidence in a high-prevalence endemic area?

Plos.org 
En

by Yalda Jafari, Oliver J. Brady, Joseph R. Briggs, Le Thuy Lien, Huynh Kim Mai, Hien Anh Thi Nguyen, Marnix Van Loock, Guillermo Herrera-Taracena, Joris Menten, Chihiro Iwasaki, Mizuki Takegata, Noriko Kitamura, Hung Do Thai, Bui Xuan Minh, Kouichi Morita, Dang Duc Anh, Sam Clifford, Kiesha Prem, Julius Hafalla, W. John Edmunds, Lay Myint Yoshida, Martin L. Hibberd, Stéphane Hué

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Knowledge, attitude, and practices of veterinarians towards canine vector-borne pathogens in Sri Lanka

Plos.org 
En

by Ushani Atapattu, Vito Colella, Rebecca J. Traub, Anke Wiethoelter

Canine vector-borne pathogens (CVBP) have a worldwide distribution and show a high prevalence in tropical countries such as Sri Lanka. Some CVBP are zoonotic, with dogs identified as reservoir hosts for human subcutaneous dirofilariasis and potentially for spotted fever rickettsioses and re-emergent brugian filariasis in Sri Lanka, making these pathogens emerging public health issues in the country. Veterinarians are crucial in monitoring... Читать дальше...

Reassessing the modularity of gene co-expression networks using the Stochastic Block Model

Plos.org 
En

by Diogo Melo, Luisa F. Pallares, Julien F. Ayroles

Finding communities in gene co-expression networks is a common first step toward extracting biological insight from these complex datasets. Most community detection algorithms expect genes to be organized into assortative modules, that is, groups of genes that are more associated with each other than with genes in other groups. While it is reasonable to expect that these modules exist, using methods that assume they exist a priori is risky... Читать дальше...

Detecting and quantifying heterogeneity in susceptibility using contact tracing data

Plos.org 
En

by Beth M. Tuschhoff, David A. Kennedy

The presence of heterogeneity in susceptibility, differences between hosts in their likelihood of becoming infected, can fundamentally alter disease dynamics and public health responses, for example, by changing the final epidemic size, the duration of an epidemic, and even the vaccination threshold required to achieve herd immunity. Yet, heterogeneity in susceptibility is notoriously difficult to detect and measure, especially early in an epidemic.... Читать дальше...

FURNA: A database for functional annotations of RNA structures

Plos.org 
En

by Chengxin Zhang, Lydia Freddolino

Despite the increasing number of 3D RNA structures in the Protein Data Bank, the majority of experimental RNA structures lack thorough functional annotations. As the significance of the functional roles played by noncoding RNAs becomes increasingly apparent, comprehensive annotation of RNA function is becoming a pressing concern. In response to this need, we have developed FURNA (Functions of RNAs), the first database for experimental RNA structures that... Читать дальше...