What to Do About Spider Veins on Your Face
Electrodessication and lasers could help. Here are some solutions.
Electrodessication and lasers could help. Here are some solutions.
An eye-opening talk was given to Cannock and District Ladies Probus Club, when Finn (previously a Puppy Walker), shared the journey of a guide dog. Guide Dogs for The Blind Association, now known as Guide Dogs, formed after WW1 when servicemen returned blind.
A trio of physicists and oceanologists, two with the University of Cologne's Institute of Geophysics and Meteorology and the third with the GEOMAR Helmholtz Center for Ocean Research Kiel, all in Germany, has found via the CESM1 climate model that an extreme El Niño tipping point could be reached in the coming decades under current emissions.
A recent study by scientists from China and Belgium suggests that deep beneath the surface of Mercury, there may be a thick layer of diamond.
Australia’s financial intelligence agency is increasingly concerned with the use of luxury jewellery and watches as a means for money laundering.
There’s been another twist in the investigation of the heist of millions of dollars of gold from the Toronto Pearson Airport in April of the past year.
The Swatch Group has reported a significant decline in revenue across the first six months of the financial year, which was attributed to economic challenges in Asia.
In recent weeks, rumours have circulated that Louis Vuitton Moët Hennessy (LVMH) is preparing a bid to become the official timekeeper for Formula 1.
As the anticipation for the International Jewellery Fair continues to build, one exhibitor has planned an eye-catching giveaway.
Visitors at the upcoming Sydney Fair will have the chance to win a consultancy package that may transform their business.
The wine festival in Burgas starts on July 19 and presents over 40 wineries and distilleries A world tasting jury will select the best wines in Bulgaria at the upcoming Burgas Wine Festival on July 19. This year it includes the special representatives of the International Organization of Vine and Wine (OIV) Sophie Pallas, Director of International Relations, and Prof....
'Reynatis' Post-Launch Plans Includes Nine Free Updates - Screens
The dynamic between parents and their children is one of the most complex living things - on or off the screen. It's common to see...
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by Hashim Ali, David Noyvert, Jacqueline Hankinson, Gemma Lindsey, Aleksei Lulla, Valeria Lulla
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by Vickie A. Marshall, Elena M. Cornejo Castro, Charles A. Goodman, Nazzarena Labo, Isabella Liu, Nicholas C. Fisher, Kyle N. Moore, Ananthakrishnan Nair, Taina Immonen, Brandon F. Keele, Mark N. Polizzotto, Thomas S. Uldrick, Yunxiang Mu, Tanuja Saswat, Laurie T. Krug, Kevin M. McBride, Kathryn Lurain, Ramya Ramaswami, Robert Yarchoan, Denise Whitby
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by Masayuki Shimojima, Satoko Sugimoto, Satoshi Taniguchi, Takahiro Maeki, Tomoki Yoshikawa, Takeshi Kurosu, Shigeru Tajima, Chang-Kweng Lim, Hideki Ebihara
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by Haomin Huang, Shenghai Chang, Tao Cui, Man Huang, Jiuxin Qu, Huimin Zhang, Ting Lu, Xing Zhang, Chun Zhou, Youjun Feng
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by Youngsin Kim, Mihyung Moon, Seokwhwan Moon, Wonkyu Moon
This work investigates whether inclusion of the low-frequency components of heart sounds can increase the accuracy, sensitivity and specificity of diagnosis of cardiovascular disorders. We standardized the measurement method to minimize changes in signal characteristics. We used the Continuous Wavelet Transform to analyze changing frequency characteristics over time and to allocate frequencies appropriately between the low-frequency and audible frequency bands. Читать дальше...
by Sheela B. Abraham, Farah Al-Marzooq, Lakshman Samaranayake, Rifat Akram Hamoudi, Wan Harun Himratul-Aznita, Hany Mohamed Aly Ahmed
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by Aina Astorch-Cardona, Lionel Bertaux, Yann Denis, Alain Dolla, Céline Rommevaux
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by Mideksa Adugna Koricho, Girmaye Deye Dinsa, Nelisiwe Khuzwayo
IntroductionPerformance Based Financing (PBF) supports realization of universal health coverage by promoting bargaining between purchasers and health service providers through identifying priority services and monitoring indicators. In PBF, purchasers use health statistics and information to make decisions rather than merely reimbursing invoices. In this respect, PBF shares certain elements of strategic health purchasing. Читать дальше...
by Japan Huynh, Thi Minh Hue Phan
This study explores the effects of banking uncertainty on firms’ debt financing. Employing data from 2007 to 2022 of Vietnam–a bank-based economy, we document that banking uncertainty negatively impacts corporate debt. The impact firmly holds across various debt maturities and sources, with the most predominant driver witnessed in bank debt. We also investigate the potential underlying mechanism linking banking uncertainty to debt financing, thereby validating the working of three crucial channels... Читать дальше...
by Mira Jung, Nicole Nicholas, Scott Grindrod, Anatoly Dritschilo
Dual-targeting chromatin regulation and DNA damage repair signaling presents a promising avenue for cancer therapy. Applying rational drug design, we synthesized a potent dual-targeting small molecule, SP-1-303. Here, we report SP-1-303 as a class I isoform selective histone deacetylase (HDAC) inhibitor and an activator of the ataxia-telangiectasia mutated protein (ATM). In vitro enzymatic assays demonstrated selective inhibition of HDAC1 and HDAC3. Читать дальше...
by Mélodie A. Nasr, Annette Aldous, Jason Daniels, Christopher Joy, Eleanor Capozzi, Michelle Yang, Patricia Moriarty, Vanessa Emmanuel-Baker, Sharyn Malcolm, Stefan J. Green, Veronica Gomez-Lobo, Mimi Ghosh
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by Camilla S. A. Davan-Wetton, Trinidad Montero-Melendez
Lipofuscin is a yellow-brown pigment typically found in the lysosomes that contains a mixture of molecules including lipids, metals and misfolded proteins. The use of Sudan black B to detect lipofuscin accumulation, a well described marker of cellular senescence and ageing, was first described in 2013 by Georgakopoulou, et al. Here, we provide an optimisation of the original protocol. Firstly, we adjusted the staining methodology for increased ease of use on cultured cells. Читать дальше...