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Новости за 11.07.2024

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Modeling soybean growth: A mixed model approach

Plos.org 
En

by Maud Delattre, Yusuke Toda, Jessica Tressou, Hiroyoshi Iwata

The evaluation of plant and animal growth, separately for genetic and environmental effects, is necessary for genetic understanding and genetic improvement of environmental responses of plants and animals. We propose to extend an existing approach that combines nonlinear mixed-effects model (NLMEM) and the stochastic approximation of the Expectation-Maximization algorithm (SAEM) to analyze genetic and environmental effects on plant growth. Читать дальше...

Parameter estimation in a whole-brain network model of epilepsy: Comparison of parallel global optimization solvers

Plos.org 
En

by David R. Penas, Meysam Hashemi, Viktor K. Jirsa, Julio R. Banga

The Virtual Epileptic Patient (VEP) refers to a computer-based representation of a patient with epilepsy that combines personalized anatomical data with dynamical models of abnormal brain activities. It is capable of generating spatio-temporal seizure patterns that resemble those recorded with invasive methods such as stereoelectro EEG data, allowing for the evaluation of clinical hypotheses before planning surgery. This study... Читать дальше...

An integrative approach to protein sequence design through multiobjective optimization

Plos.org 
En

by Lu Hong, Tanja Kortemme

With recent methodological advances in the field of computational protein design, in particular those based on deep learning, there is an increasing need for frameworks that allow for coherent, direct integration of different models and objective functions into the generative design process. Here we demonstrate how evolutionary multiobjective optimization techniques can be adapted to provide such an approach. With the established Non-dominated Sorting Genetic Algorithm... Читать дальше...

Role of diffusion and reaction of the constituents in spreading of histone modification marks

Plos.org 
En

by Vinoth Manivannan, Mandar M. Inamdar, Ranjith Padinhateeri

Cells switch genes ON or OFF by altering the state of chromatin via histone modifications at specific regulatory locations along the chromatin polymer. These gene regulation processes are carried out by a network of reactions in which the histone marks spread to neighboring regions with the help of enzymes. In the literature, this spreading has been studied as a purely kinetic, non-diffusive process considering the interactions between neighboring nucleosomes. Читать дальше...

Reinforcement learning of altruistic punishment differs between cultures and across the lifespan

Plos.org 
En

by Ziyan Guo, Jialu Yu, Wenxin Wang, Patricia Lockwood, Zhen Wu

Altruistic punishment is key to establishing cooperation and maintaining social order, yet its developmental trends across cultures remain unclear. Using computational reinforcement learning models, we provided the first evidence of how social feedback dynamically influences group-biased altruistic punishment across cultures and the lifespan. Study 1 (n = 371) found that Chinese participants exhibited higher learning rates than... Читать дальше...

A phylogeny-informed characterisation of global tetrapod traits addresses data gaps and biases

Plos.org 
En

by Mario R. Moura, Karoline Ceron, Jhonny J. M. Guedes, Rosana Chen-Zhao, Yanina V. Sica, Julie Hart, Wendy Dorman, Julia M. Portmann, Pamela González-del-Pliego, Ajay Ranipeta, Alessandro Catenazzi, Fernanda P. Werneck, Luís Felipe Toledo, Nathan S. Upham, João F. R. Tonini, Timothy J. Colston, Robert Guralnick, Rauri C. K. Bowie, R. Alexander Pyron, Walter Jetz

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Future Launches Branded Content Studio to Tap New Budgets

Adweek.com 
En

Today, the media company Future launched a branded content studio, Future Creative, in hopes of bolstering its direct advertising business and preparing itself for the eventual deprecation of third-party cookies. Future, a specialist media organization, houses over 230 publishing titles, including flagship titles like Marie Claire, Who What Wear and TechRadar. The publicly traded, profitable...

How Science Can Defeat Witchcraft Fears in Papua New Guinea

Scientific American 
En

Belief in witchcraft and sorcery is deeply rooted in Papua New Guinea's culture and history, but it can lead to violence, particularly against women. Local public health experts are working to end this violence through education.

70Mai A510 review: This easy-to-install dash cam ticks all the boxes

PC World 
En

At a glance

Expert's Rating

Pros

  • Very good day captures, and decent night captures
  • Handsome design
  • Integrated GPS
  • Phone connectivity

Cons

  • Rear night captures are less than optimal
  • Phone app requires a 70Mai online account

Our Verdict

The 70Mai A510 is a very good front/rear combo for the price. The front captures are top-notch, and the rear captures aren’t too far behind.

Best Prices Today... Читать дальше...

Corujeira 113 Renovation / Impare Arquitectura

Archdaily.com 
En

The work on the old Porto Industrial Slaughterhouse, a project by Japanese architect Kengo Kuma, and the redevelopment planned for Praça da Corujeira are examples of the transformation of the city of Porto. In the near future, the eastern part of the city can respond to the current needs of a contemporary city, with qualified spaces and facilities linked to an efficient public transport network.