Новости за 18.06.2024

In Reply We are grateful to Dr Thadani and colleagues for their interest in our work and applaud their efforts to improve outcomes from AKI around the world. We agree that AKI is important to assess and treat in children with sepsis in any environment and that children in some less-resourced environments are particularly vulnerable to AKI. However, we respectfully disagree with their statement that “shortcomings void the criteria used and perpetuate the neglect of children living in these settings.”

To the Editor We read Dr Sanchez-Pinto and colleagues’ study with interest, but we are concerned that the final Phoenix 4-organ model does not include acute kidney injury (AKI) assessment. Additionally, the Phoenix 8-organ model used only a single serum creatinine threshold. Despite inclusion of data from low- and middle-income countries, these shortcomings void the clinical utility of these criteria and perpetuate the neglect of children living in these settings.

This cross-sectional study uses data from retail pharmacies to examine shingles vaccine uptake among Medicare Part D beneficiaries following an IRA policy to eliminate cost sharing.

Without a dissenting vote, the House of Delegates of the American Medical Association adopted last week a resolution calling on the Board of Trustees to use its best endeavors to have repealed such sections of the national prohibition acts as may interfere with the proper relation between the physician and his patient in prescribing alcohol medicinally. The resolution has been greeted by the press of the country with general approval. Most of the Chicago newspapers have already expressed themselves editorially... Читать дальше...

US public health preparedness and response to highly pathogenic avian influenza A(H5N1) viruses are assessed in this survey study conducted by the CDC.

This Medical News article is an interview with Saurabh Jha, a cardiothoracic radiologist and an associate professor of radiology at the University of Pennsylvania, and JAMA Editor in Chief Kirsten Bibbins-Domingo.

Current strategies to protect children from malaria—administration of new RTS,S/AS01 or R21/Matrix-M vaccines as well as seasonal medications—require about 20 health care visits by the time a child reaches age 5 years. However, an approach involving the annual administration of a monoclonal antibody might provide similar malaria protection while reducing health care visits, a randomized clinical trial found.

Intradermal injections that were one-fifth of the standard mpox vaccine dose generated antibody responses equivalent to those of subcutaneous injections of the standard dose at 6 weeks, based on results from 225 US adults aged 18 to 50 years. No participants experienced serious adverse events related to the vaccine.

The proportion of people who die while pregnant or within 42 days after their pregnancy ends has been steadily increasing in the US. Now, updated numbers from the National Vital Statistics System indicate promising trends in maternal mortality rates. About 22 people per 100 000 live births died of pregnancy-related causes in 2022, down from about 33 per 100 000 in 2021. Although maternal mortality rates declined for Black, Hispanic, and White people, Black people died of pregnancy-related causes... Читать дальше...

Although heart failure mortality rates fell between 1999 and 2012, the proportion of people dying from the condition in the US has increased in recent years, according to a study published in JAMA Cardiology. By 2021, the heart failure mortality rate was higher than in 1999, signaling that earlier improvements have been “entirely undone” over the past 10 years, the researchers wrote. The findings were based on death certificate data collected by the US Centers for Disease Control and Prevention.

The US Food and Drug Administration recently approved pivmecillinam, sold as Pivya, for uncomplicated urinary tract infections (UTIs) in females aged 18 years or older with no structural abnormalities of their urinary tract. UTIs affect about 50% of females at some point during their life, the FDA noted.

Long-term Veterans Health Administration (VA) nursing home residents who started new medications to treat high blood pressure were more than twice as likely to experience a fracture than those who did not, according to a cohort study involving more than 29 600 VA participants, almost all male, aged 65 years or older.

Up to 45% of physicians are subject to noncompete clauses, contractual requirements that can prevent them from changing jobs, which can limit competition and access to care, according to the American Medical Association. However, employers will no longer be allowed to enforce noncompete clauses as of August, when a final rule issued by the Federal Trade Commission (FTC) banning noncompete clauses goes into effect. The move will reduce health care costs by up to $194 billion over the next 10 years, the FTC predicted.

People who received a microneedle patch that delivered a measles and rubella vaccine mounted immune responses that were equivalent to those vaccinated via subcutaneous injection, according to data from a randomized clinical trial involving 285 participants from The Gambia, including 240 toddlers and infants. The results are the first to support microneedle patches as a safe and effective way to administer the vaccine to children, the researchers noted in The Lancet.

The US Food and Drug Administration (FDA) granted emergency use authorization to pemivibart, marketed as Pemgarda, to protect people who are immunocompromised from COVID-19. Pemivibart is the only long-acting monoclonal antibody available in the US for preexposure prophylaxis after the FDA revoked authorization of tixagevimab copackaged with cilgavimab, also known as Evusheld, in January 2023.

Decheng Capital Eyes $700M Raise for Fifth Life Sciences Fund as VC Heats Up 6/18/2024

Roche Inks Potential $1.8B Deal With Ascidian to Develop RNA Exon Therapies 6/18/2024

GSK Reignites Blenrep Blockbuster Aspirations With Data from Phase III Studies 6/18/2024

Merck Wins FDA Approval for First Pneumococcal Vaccine Designed for Adults 6/18/2024

AstraZeneca’s Truqap Flops in Phase III Triple-Negative Breast Cancer Trial 6/18/2024

Zentalis Hit With FDA Partial Clinical Hold on Cancer Studies After Patient D... 6/18/2024

Date: 06/18/2024
Player: Vincent Llorca (D)
From: Angers
To: Angers
Information: 1 year
Source: You need a free account to view Transfer URL Sign In/Up

Date: 06/18/2024
Player: Théo Caubet (D)
From: Montpellier
To: Montpellier
Information: 1 year
Source: You need a free account to view Transfer URL Sign In/Up

Date: 06/18/2024
Player: Victor Thery (F)
From: Châlons-en-Champagne
To: Châlons-en-Champagne
Information: 1 year
Source: You need a free account to view Transfer URL Sign In/Up

Date: 06/18/2024
Player: Yuri Cristellon (F)
From: Gherdëina
To: Gherdëina
Information: 1 year
Source: You need a free account to view Transfer URL Sign In/Up