ru24.pro
News in English
Июнь
2024

Новости за 14.06.2024

Interplay between Pitx2 and Pax7 temporally governs specification of extraocular muscle stem cells

Plos.org 

by Mao Kuriki, Amaury Korb, Glenda Comai, Shahragim Tajbakhsh

Gene regulatory networks that act upstream of skeletal muscle fate determinants are distinct in different anatomical locations. Despite recent efforts, a clear understanding of the cascade of events underlying the emergence and maintenance of the stem cell pool in specific muscle groups remains unresolved and debated. Here, we invalidated Pitx2 with multiple Cre-driver mice prenatally, postnatally, and during lineage progression. Читать дальше...

Threshold-awareness in adaptive cancer therapy

Plos.org 

by MingYi Wang, Jacob G. Scott, Alexander Vladimirsky

Although adaptive cancer therapy shows promise in integrating evolutionary dynamics into treatment scheduling, the stochastic nature of cancer evolution has seldom been taken into account. Various sources of random perturbations can impact the evolution of heterogeneous tumors, making performance metrics of any treatment policy random as well. In this paper, we propose an efficient method for selecting optimal adaptive treatment policies under randomly evolving tumor dynamics. Читать дальше...

mbtransfer: Microbiome intervention analysis using transfer functions and mirror statistics

Plos.org 

by Kris Sankaran, Pratheepa Jeganathan

Time series studies of microbiome interventions provide valuable data about microbial ecosystem structure. Unfortunately, existing models of microbial community dynamics have limited temporal memory and expressivity, relying on Markov or linearity assumptions. To address this, we introduce a new class of models based on transfer functions. These models learn impulse responses, capturing the potentially delayed effects of environmental changes on the microbial community. Читать дальше...

How to spot the ISS

The Planetary Society 

Seeing the ISS is easy and amazing stargazing.

Debate Rages Over Global Oil Demand

Oilprice.com 

Signs that inflation may be easing in the U.S. have given oil markets a bullish hue this week, but uncertainty over demand remains.Friday, June 14, 2024After several weeks of unpredictable see-sawing, oil markets are back to their usual self. The IEA and OPEC are publicly arguing about the future of oil demand, U.S. interest rate cuts are still not happening, and questions remain about the strength of summer gasoline demand. That said, a positive outlook in U.S. inflation data might have helped to... Читать дальше...

The Gayest Cars In The Los Angeles Pride Parade Ranked

Jalopnik.com 

Queer folks love cars. I’m a part of a friend group with a lot of self-proclaimed car gays, and when you work in the automotive world you quickly learn that it’s a very queer space. That was a pleasant surprise for me when I first joined Mercedes-Benz Research and Development as a test driver years ago, and the longer…

Читать дальше...