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Новости за 14.06.2024

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Incorporating transportation costs into the single and multiple items newsvendor problems

Plos.org 
En

by Moncer Hariga

The efficiency and responsiveness of supply chains are vitally dependent on inventory replenishment and transportation decisions. In this paper, we study a supply chain consisting of a single retailer ordering seasonal products within the newsvendor framework. The primary objective of the paper is to investigate the retailer’s decision-making process, aimed at determining the optimal replenishment quantities and selecting the appropriate mix and size of the truck fleet. Initially... Читать дальше...

Isolation and screening of fungi for enhanced agarwood formation in Aquilaria sinensis trees

Plos.org 
En

by Chuang Liu, Guoying Zhou, Junang Liu

Agarwood is a resinous heartwood of Aquilaria sinensis that is formed in response to mechanical wounding. In the present study pre-treatment of Aquilaria sinensis was carried out, and then the dominant fungi were isolated and purified from the surface and electroshock holes of trees. The isolated Trichoderma sp. and Neurospora sp. were then screened for resistance against benzyl acetone and then inoculated into healthy Aquilaria sinensis trees. After six months... Читать дальше...

Understanding interaction in problematic dementia and social care encounters: Protocol for a micro-level study combining video-ethnography and Conversation Analysis (CA)

Plos.org 
En

by John Chatwin, Katherine Ludwin, Danielle Jones, Alison Bravington

Introduction

It is well established that the actions and behaviour of dementia care workers are fundamental to the wellbeing of the people they care for. Not only do they deal with basic healthcare needs, but they also perform a vital psycho-social function by providing–through their regular presence–an underlying continuity for residents. This has been shown to improve well-being, particularly for those in the advanced stages of dementia. Читать дальше...

Dynamics of a stochastic SEIQR model driven by Lévy jumps with bilinear incidence rates

Plos.org 
En

by Qiuye Xia, Xiaoling Qiu

In this study, we propose a stochastic SEIQR infectious disease model driven by Lévy noise. Firstly, we study the existence and uniqueness of the global positive solution of the model by using the stop-time. Secondly, the asymptotic behavior of the stochastic system at disease-free equilibrium and endemic equilibrium are discussed. Then, the sufficient condition for persistence under the time mean is studied. Finally, our theoretical results are verified by numerical simulation.

Prospective observational study of peripheral intravenous cannula utilisation and frequency of intravenous fluid delivery in the emergency department—Convenience or necessity?

Plos.org 
En

by Michael Willis, Efrem Colonetti, Ali Bakir, Yousef Jamal Alame, Megan Annetts, Deren T. Aygin, Amina Daou, Sultan Farooq, Nicholas A. Fine, Gozde Firat, Benjamin Goozee, Anuj Neelesh Gupta, Charlotte Hubbett, Nicole Shun Yee Loi, Laura Maciejec-Biskup, Merline Gabriela Muthukumar, Jason Pott, Benjamin M. Bloom, Maria Lorenza Muiesan, Tim Harris

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Diazepam inhibits LPS-induced pyroptosis and inflammation and alleviates pulmonary fibrosis in mice by regulating the let-7a-5p/MYD88 axis

Plos.org 
En

by Duanyi Song, Xuefang Tang, Juan Du, Kang Tao, Yun Li

Background and objective

Pulmonary fibrosis caused by lung injury is accompanied by varying degrees of inflammation, and diazepam can reduce the levels of inflammatory factors. Therefore, the purpose of this study was to determine whether diazepam can inhibit inflammation and ameliorate pulmonary fibrosis by regulating the let-7a-5p/myeloid differentiation factor 88 (MYD88) axis.

Methods

Lipopolysaccharide (LPS) was used to... Читать дальше...

Integrating Embodied Social Presence Theory and Process Virtualization Theory to assess business process virtualizability: The mediating role of embodied co-presence

Plos.org 
En

by Juan Yang, Hualong Fang

In the digital era, the integration of technology within business processes is pivotal for organizational efficiency. This study investigates the impact of IT characteristics-specifically IT representation, IT reach, and monitoring capability-on the virtualizability of business processes, utilizing the frameworks of Embodied Social Presence Theory (ESPT) and Process Virtualization Theory (PVT). Our objective is to explore how these IT characteristics, through the mediation of embodied co-presence... Читать дальше...

Strategies for launching streaming content: Assessing movie-country relatedness and its impact on international popularity

Plos.org 
En

by Changjun Lee, Sung Wook Ji

The study proposes a way to measure the relatedness between countries and movies (movie—country relatedness density) and to test whether this relatedness is an important factor in predicting the popularity of a movie in a certain country. The results show that both movie—country relatedness density and movie ubiquity (i.e., popularity across many countries) are positively associated with a movie appearing in a country’s top 20 list even after considering other covariates. Читать дальше...

Whether academics’ job performance makes a difference to burnout and the effect of psychological counselling—comparison of four types of performers

Plos.org 
En

by Miao Lei, Gazi Mahabubul Alam, Karima Bashir, Gui Pingping

Treating burnout as an independent variable while performance is the dependent variable, earlier studies revealed that job burnout experienced by academics adversely affects how well they perform. Whether performance may contribute to the emergence of burnout is yet to be analyzed—it is an issue investigated in this paper. Readjusting the nature of the variables, this quantitative study adopted group regression and it discovered... Читать дальше...

A misleading tail: A long-term study of reptile responses to multiple disturbances undermined by a change in surveying techniques

Plos.org 
En

by Maldwyn John Evans, Christopher MacGregor, David Lindenmayer

Long-term ecological monitoring is crucial to understanding the complex dynamics of ecosystems, communities, and populations. Despite this, monitoring data are lacking or rare for the vast majority of biodiversity. Here we report the results of 19 years (2003–2022) of continuous annual monitoring of reptile species at Booderee National Park (BNP) on the east coast of south-eastern Australia. We tested the effects of time, habitat type... Читать дальше...

Reinterpretation of the results of randomized clinical trials

Plos.org 
En

by Farrokh Habibzadeh

Background

Randomized clinical trials (RCTs) shape our clinical practice. Several studies report a mediocre replicability rate of the studied RCTs. Many researchers believe that the relatively low replication rate of RCTs is attributed to the high p value significance threshold. To solve this problem, some researchers proposed using a lower threshold, which is inevitably associated with a decrease in the study power.

Methods

The results of 22 500 RCTs retrieved... Читать дальше...

May DNA analyses be biased by hidden oxidative damage? Voltammetric study of temperature and oxidation stress effect

Plos.org 
En

by Oskar Szczepaniak, Marta Ligaj

The analysis of nucleic acids is one of the fundamental parts of modern molecular biology and molecular diagnostics. The information collected predominantly depends on the condition of the genetic material. All potential damage induced by oxidative stress may affect the final results of the analysis of genetic material obtained using commonly used techniques such as polymerase chain reaction or sequencing. The aim of this work was to evaluate the effects... Читать дальше...