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Новости за 20.05.2024

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Determinants of social participation in people with disability

Plos.org 
En

by Tugce Pasin, Bilinc Dogruoz Karatekin

Purpose

In this study, it is aimed to determine personal wellbeing and social participation levels across different physical disability types and levels of mobility.

Methods

A sample of 85 individuals with physical disabilities, excluding those with mental disabilities were included. Sociodemographics, mobility of the participants, cause, duration of disability were recorded. Personal Wellbeing Index-Adult (PWI-A) scale was used for the assessment... Читать дальше...

Assessing the reduction of viral infectivity in HPV16/18-positive women after one, two, and three doses of Gardasil-9 (RIFT): Study protocol

Plos.org 
En

by Victoria López-Codony, Álvaro de Andrés-Pablo, Angelica Ferrando-Díez, Maria Eulàlia Fernández-Montolí, Marta López-Querol, Sara Tous, Carlos Ortega-Expósito, Juan Carlos Torrejón-Becerra, Yolanda Pérez, Anna Ferrer-Artola, Josep Maria Sole-Sedeno, Clara Grau, Blas Rupérez, Maria Saumoy, Mónica Sánchez, Paula Peremiquel-Trillas, Laia Bruni, Laia Alemany, Francesc Xavier Bosch, Miquel Angel Pavón

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C-reactive protein and high-sensitivity C-reactive protein levels in asymptomatic intestinal parasite carriers from urban and rural areas of Gabon

Plos.org 
En

by Helena Noéline Kono, Mérédith Flore Ada Mengome, Bedrich Pongui Ngondza, Roger Hadry Sibi Matotou, Luccheri Ndong Akomezoghe, Bernadette Ekomi, Bridy Chesly Moutombi Ditombi, Jeanne Vanessa Koumba Lengongo, Jacques Mari Ndong Ngomo, Noé Patrick M’Bondoukwé, Cyrille Bisseye, Denise Patricia Mawili-Mboumba, Marielle Karine Bouyou Akotet

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Dynamics of emergence and genetic diversity of dengue virus in Reunion Island from 2012 to 2022

Plos.org 
En

by Etienne Frumence, David A. Wilkinson, Raphaelle Klitting, Muriel Vincent, Nicolas Mnemosyme, Gilda Grard, Nicolas Traversier, Ghislaine Li-Pat-Yuen, Diana Heaugwane, Laurent Souply, Claude Giry, Marie-Claire Paty, Louis Collet, Local Laboratory Network , Patrick Gérardin, Fabian Thouillot, Xavier De Lamballerie, Marie-Christine Jaffar-Bandjee

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Bridging the gap between the evolutionary dynamics and the molecular mechanisms of meiosis: A model based exploration of the PRDM9 intra-genomic Red Queen

Plos.org 
En

by Alice Genestier, Laurent Duret, Nicolas Lartillot

Molecular dissection of meiotic recombination in mammals, combined with population-genetic and comparative studies, have revealed a complex evolutionary dynamic characterized by short-lived recombination hotspots. Hotspots are chromosome positions containing DNA sequences where the protein PRDM9 can bind and cause crossing-over. To explain these fast evolutionary dynamic, a so-called intra-genomic Red Queen model has been proposed, based... Читать дальше...

Queuosine biosynthetic enzyme, QueE moonlights as a cell division regulator

Plos.org 
En

by Samuel A. Adeleye, Srujana S. Yadavalli

In many organisms, stress responses to adverse environments can trigger secondary functions of certain proteins by altering protein levels, localization, activity, or interaction partners. Escherichia coli cells respond to the presence of specific cationic antimicrobial peptides by strongly activating the PhoQ/PhoP two-component signaling system, which regulates genes important for growth under this stress. As part of this pathway, a biosynthetic enzyme called QueE... Читать дальше...

Interpretable metric learning in comparative metagenomics: The adaptive Haar-like distance

Plos.org 
En

by Evan D. Gorman, Manuel E. Lladser

Random forests have emerged as a promising tool in comparative metagenomics because they can predict environmental characteristics based on microbial composition in datasets where β-diversity metrics fall short of revealing meaningful relationships between samples. Nevertheless, despite this efficacy, they lack biological insight in tandem with their predictions, potentially hindering scientific advancement. To overcome this limitation, we leverage a geometric... Читать дальше...