Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage
by Nidhi Shukla, Sarah M. Roelle, John C. Snell, Olivia DelSignore, Anna M. Bruchez, Kenneth A. Matreyek
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by Nidhi Shukla, Sarah M. Roelle, John C. Snell, Olivia DelSignore, Anna M. Bruchez, Kenneth A. Matreyek
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by Jessica Ciesla, Kai-Lieh Huang, Eric J. Wagner, Joshua Munger
Viral disruption of innate immune signaling is a critical determinant of productive infection. The Human Cytomegalovirus (HCMV) UL26 protein prevents anti-viral gene expression during infection, yet the mechanisms involved are unclear. We used TurboID-driven proximity proteomics to identify putative UL26 interacting proteins during infection to address this issue. We find that UL26 forms a complex with several immuno-regulatory proteins... Читать дальше...
by Kush K. Yadav, Patricia A. Boley, Thamonpan Laocharoensuk, Saroj Khatiwada, Carolyn M. Lee, Menuka Bhandari, Lindsey Moore, Juliette Hanson, Scott P. Kenney
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by Amanda O. Shaver, Isabella R. Miller, Etta S. Schaye, Nicolas D. Moya, J. B. Collins, Janneke Wit, Alyssa H. Blanco, Fiona M. Shao, Elliot J. Andersen, Sharik A. Khan, Gracie Paredes, Erik C. Andersen
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by Chengli Wen, Xu Zhang, Yong Li, Wanmeng Xiao, Qinxue Hu, Xianying Lei, Tao Xu, Sicheng Liang, Xiaolan Gao, Chao Zhang, Zehui Yu, Muhan Lü
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by Duc Hong Vo, Anh The Vo, Co Thi-Huyen Dinh, Ngoc Phu Tran
In the digital age, firms should continually innovate and adapt to remain competitive and enhance performance. Innovation and adaptation require firms to take a holistic approach to their corporate structuring to ensure efficiency and effectiveness to stay competitive. This study examines how corporate restructuring impacts firm performance in Vietnam. We then investigate the moderating role of digital transformation in the corporate restructuring–firm performance nexus. Читать дальше...
by Yan Liu, Chao Zhang, Yuda Wang, Xiaofu Luo, Guangtao Liu, Zizhe Zhang, Jianyong Shen
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by Samuel T. Chatio, Enyonam Duah, Lucy O. Ababio, Nicola Lister, Olufolake Egbujo, Kwaku Marfo, Raymond Aborigo, Patrick Ansah, Isaac Odame
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by Kamonchanok Sairat, Nitikorn Phoosuwan
BackgroundOral healthcare behavior determines oral health status and the incidence of oral diseases. People with type 2 diabetes mellitus (T2DM) are at-risk of having low oral healthcare behavior and disease-related oral health.
ObjectiveTo investigate the oral health status and factors associated with oral healthcare behavior among people with T2DM in Thailand.
MethodsIn total, 401 people with T2DM participated in the study based... Читать дальше...
by Avner Hatsek, Irit Hochberg, Deeb Daoud Naccache, Aya Biderman, Yuval Shahar
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by Sen Tian, Liangfo Zhao
Public tolerance for corruption within a society significantly influences the prevalence of corrupt practices, but less is known about how this tolerance evolves with social norms. This paper presents experimental evidences demonstrating that the descriptive social norm indicating widespread corruption can lead to increased tolerance for corruptive acts. We introduce an asymmetric information ultimatum game to simulate the interactions between embezzlers and citizens. Читать дальше...
by Dinesh S. Chandel, Wesley A. Tom, Chao Jiang, Gary Krzyzanowski, Nirmalee Fernando, Appolinaire Olou, M. Rohan Fernando
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by Ernest Yorke, Josephine Akpalu, Gwendolyn de-Graft Johnson, Yacoba Atiase, Margaret Reynolds, Ruth Laryea, John Tetteh, Alfred E. Yawson, Albert G. B. Amoah
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by Violeta Magdalena Rojas Huayta, Rebecca Pradeilles, Hilary M. Creed-Kanashiro, Emily Rousham, Doris Delgado, Rossina Pareja, Edwige Landais, Nervo Verdezoto, Emma Haycraft, Michelle Holdsworth
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by David Soriano, Rafael Tarragó, Daniel Lapresa, Mike Callan, Xavier Iglesias
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by Binbin Du, Jia Wu, Qingming Wang, Chaoyue Sun, Genlou Sun, Jie Zhou, Lei Zhang, Qingsong Xiong, Xifeng Ren, Baowei Lu
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by Kyung Hye Lee, Min-Young Song, Sora Lee, JinSun Park, Jung Hee Kang, Haneul Cho, Ki-Bum Kim, Soo Ji Son, Xian Wu Cheng, Young Ju Lee, Gi-Ja Lee, Jae Ho Shin, Weon Kim
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by Elena Cubero, Ana Ruano, Aida Delgado, Xavier Barril, Sara Morales, Ana Trapero, Lorenzo Leoni, Manolo Bellotto, Roberto Maj, Beatriz Calvo-Flores Guzmán, Natalia Pérez-Carmona, Ana Maria Garcia-Collazo
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by Fernando Barrios Aguirre, Diana Maritza Alvarez Ovalle, Nancy Milena Riveros Chávez, Carla Johana Martinez Garcia
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by R. Constance Wiener, Christopher Waters, Ruchi Bhandari
IntroductionPeople make oral healthcare decisions regardless of having partial information, misinformation, sources that deliberately mislead, or information that is culturally influenced. This is particularly true in the Appalachian culture where oral healthcare decision-making practices are not well understood by researchers and dental professionals. Despite efforts to improve dental care utilization, the Appalachia region remains low in oral healthcare utilization. Читать дальше...
by Shotaro Otsuka, Ryoma Matsuzaki, Shogo Kakimoto, Yuta Tachibe, Takuya Kawatani, Seiya Takada, Akira Tani, Kazuki Nakanishi, Teruki Matsuoka, Yuki Kato, Masaki Inadome, Nao Nojima, Harutoshi Sakakima, Keita Mizuno, Yosuke Matsubara, Ikuro Maruyama
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by Arata Inoue, Eiko Koike, Naoyuki Maeda, Chota Matsumoto
PurposeRandom noise-moving images (noises) can make glaucoma patients with no subjective symptoms aware of visual field abnormalities. To explore this concept, we developed a noise using computer graphics (CG) and investigated the difference in the subjective perception of visual field abnormalities between CG and conventional analog noises.
MethodsWe enrolled individuals with glaucoma (205 eyes), preperimetric glaucoma (PPG; 19 eyes), and normal eyes (35 eyes). Читать дальше...
by Julius Möttönen, Ville T. Ponkilainen, Ville M. Mattila, Ilari Kuitunen
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by Yeji Kim, Chul Gu Kim, Jong Woo Kim, Kyungdo Han, Jae Hui Kim
This study aimed to investigate the impact of the cumulative burden of metabolic syndrome (MetS) on the incidence of retinal vein occlusion (RVO) in young adults. We included 1,408,093 subjects aged ≥20 and
by Gregory Laynor, Elizabeth R. Stevens
BackgroundMeta-research in which researchers are the study subjects can illuminate how to better support researchers and enhance the development of research capacity. Comprehensively compiling the literature in this area can help define best practices for research capacity development and reveal gaps in the literature. However, there are challenges to assessing and synthesizing the breadth of the meta-research literature produced.
MethodsIn this article... Читать дальше...