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Новости за 15.05.2024

Exploring the mechanism behind drug eruptions in the skin

Sciencedaily.com 

Although drug eruptions are often linked to the human leukocyte antigen (HLA), the mechanism of its involvement in presenting symptoms of the skin remains unclear. In a recent study, researchers used genetically engineered mice to demonstrate the role of HLA in mediating intracellular reactions in keratinocytes, leading to drug eruptions in the skin. Their findings could lead to improved preventive and treatment measures for drug eruptions.

Fighting fat and inflammation: Scientists develop powerful new compounds

Sciencedaily.com 

Obesity and inflammatory diseases are increasing in prevalence and contribute to the growing burden of lifestyle disorders such as diabetes and hypertension. There is a lack of naturally derived alternatives to tackle these issues. Researchers have synthesized novel amino acid derivatives of menthol and studied its properties. The menthyl esters showed exceptional anti-inflammatory and anti-obesity activities during preclinical studies and can be developed as therapeutic compounds with further research.

Polyglycerol coating: A breakthrough in safer nanoparticle environmental remediation

Sciencedaily.com 

Engineered nanoparticles (NPs), commonly utilized in environmental remediation, can pose significant toxicity risks upon ingestion by organisms. Researchers have now devised a solution to this challenge by creating a hydrophilic coating, utilizing polyglycerol (PG) functionalization, for NPs. This coating effectively prevents NP aggregation inside organisms' bodies and facilitates easier passage, thereby reducing accumulation. Applicable to various NPs, the novel surface functionalization approach... Читать дальше...

Climate change is most prominent threat to pollinators

Sciencedaily.com 

A new article has found that climate change is the most prominent threat to pollinators -- such as bumblebees, wasps, and butterflies -- who are essential for biodiversity conservation, crop yields and food security. The research suggests that many of the threats to pollinators result from human activities.

Drug compounds to combat neurodegenerative diseases

Sciencedaily.com 

Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins. Prion disease is an umbrella term for a group of fatal and currently untreatable neurodegenerative diseases that not only affect humans, but also wild and captive animals. These diseases include Creutzfeldt-Jakob disease (CJD) in humans, bovine spongiform encephalopathy (BSE, or 'mad cow disease'), and chronic wasting disease (CWD) affecting deer, elk and moose.

Alzheimer's disease without symptoms: How is that possible?

Sciencedaily.com 

Everyone experiences aging in their own way, and factors such as genetics, lifestyle and environment play a role in this process. Some individuals reach the age of 90 or even 100 in good health, without medications or brain disease. But how do these individuals maintain their health as they age?

An astrocytic pH regulator that can repair the blood-brain barrier and reverse brain damage caused by ischemic stroke

Sciencedaily.com 

A recent study has found that an ion transporter protein that regulates the pH of specific brain cells can repair the blood-brain barrier and restore normal brain function after ischemic stroke. The study has revealed novel and specific therapeutic targets for ischemic stroke and related brain conditions for which no targeted treatments exist currently.

Researchers use artificial intelligence to boost image quality of metalens camera

Sciencedaily.com 

Researchers have leveraged deep learning techniques to enhance the image quality of a metalens camera. The new approach uses artificial intelligence to turn low-quality images into high-quality ones, which could make these cameras viable for a multitude of imaging tasks including intricate microscopy applications and mobile devices.

A simple quantum internet with significant possibilities

Sciencedaily.com 

It's one thing to dream up a quantum internet that could send hacker-proof information around the world via photons superimposed in different quantum states. It's quite another to physically show it's possible. That's exactly what physicists have done, using existing Boston-area telecommunication fiber, in a demonstration of the world's longest fiber distance between two quantum memory nodes to date.

Iconic baobabs: The origin and long-distance travels of upside down trees

Sciencedaily.com 

The research cracks the code on the iconic baobab tree's origin story, revealing their surprising origins in Madagascar and incredible long-distance dispersals to Africa and Australia. The study unveils how baobabs developed unique pollination mechanisms -- some attracting hawkmoths, others lemurs, and even bats -- showcasing remarkable evolutionary adaptations. The research sheds light on how climate change has shaped the baobab's distribution and diversification over millions of years, offering... Читать дальше...