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Новости за 14.05.2024

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Distribution and dynamics of Anopheles gambiae s.l. larval habitats in three Senegalese cities with high urban malaria incidence

Plos.org 
En

by Fatou Ndiaye, Abdoulaye Diop, Joseph Chabi, Katherine Sturm-Ramirez, Massila Senghor, El Hadji Diouf, Badara Samb, Seynabou Mocote Diedhiou, Omar Thiaw, Sarah Zohdy, Ellen Dotson, Doudou Sene, Mame Birame Diouf, Valerie Koscelnik, Lilia Gerberg, Abdoulaye Bangoura, Tiffany Clark, Ousmane Faye, Ibrahima Dia, Lassana Konate, El Hadji Amadou Niang

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Investigating the effect of anatomical variations in the response of the neonatal brachial plexus to applied force: Use of a two-dimensional finite element model

Plos.org 
En

by Sarah J. Wright, Michele J. Grimm

The brachial plexus is a set of nerves that innervate the upper extremity and may become injured during the birthing process through an injury known as Neonatal Brachial Plexus Palsy. Studying the mechanisms of these injuries on infant cadavers is challenging due to the justifiable sensitivity surrounding testing. Thus, these specimens are generally unavailable to be used to investigate variations in brachial plexus injury mechanisms. Finite Element Models... Читать дальше...

Effect of paternal-maternal parenting styles on college students’ internet addiction of different genders: The mediating role of life satisfaction

Plos.org 
En

by Zixin Liu, Hui Cheng, Hexu Guan, Xi Yang, Zi Chen

This study aimed to understand the current situation of paternal-maternal parenting style, life satisfaction, and internet addiction among college students and explored the influence of paternal-maternal parenting styles and life satisfaction on the internet addiction of male and female college students. A questionnaire survey was administered to 967 college students in China. Life satisfaction partially mediated the effect of the paternal-maternal... Читать дальше...

Transcriptomics analysis highlights potential ways in human pathogenesis in Leishmania braziliensis infected with the viral endosymbiont LRV1

Plos.org 
En

by Kátia Paula Felipin, Mauro Valentino Paloschi, Milena Daniela Souza Silva, Yoda Janaina Ikenohuchi, Hallison Mota Santana, Sulamita da Silva Setúbal, Cristina Matiele Alves Rego, Jéssica Amaral Lopes, Charles Nunes Boeno, Suzanne Nery Serrath, Enmanuella Helga Ratier Terceiro De Medeiros, Iasmin Ferreira Pimentel, Antonio Edson Rocha Oliveira, Elisa Cupolillo, Lilian Motta Cantanhêde, Ricardo de Godoi Matos Ferreira, Juliana Pavan Zuliani

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The Hog1 MAPK substrate governs Candida glabrata-epithelial cell adhesion via the histone H2A variant

Plos.org 
En

by Mahima Sagar Sahu, Rajaram Purushotham, Rupinder Kaur

CgHog1, terminal kinase of the high-osmolarity glycerol signalling pathway, orchestrates cellular response to multiple external stimuli including surplus-environmental iron in the human fungal pathogen Candida glabrata (Cg). However, CgHog1 substrates remain unidentified. Here, we show that CgHog1 adversely affects Cg adherence to host stomach and kidney epithelial cells in vitro, but promotes Cg survival in the iron-rich gastrointestinal tract niche. Читать дальше...

A role for the C. elegans Argonaute protein CSR-1 in small nuclear RNA 3’ processing

Plos.org 
En

by Brandon M. Waddell, Cheng-Wei Wu

The Integrator is a multi-subunit protein complex that catalyzes the maturation of snRNA transcripts via 3’ cleavage, a step required for snRNA incorporation with snRNP for spliceosome biogenesis. Here we developed a GFP based in vivo snRNA misprocessing reporter as a readout of Integrator function and performed a genome-wide RNAi screen for Integrator regulators. We found that loss of the Argonaute encoding csr-1 gene resulted in widespread 3’ misprocessing... Читать дальше...

What Is The Best Factory Option Ever Offered On A Car?

Jalopnik.com 
En

Back when I bought my E39 BMW 540i, it had basically everything I was looking for at the time. A torquey naturally aspirated V8, a manual transmission, rear-wheel drive and a tape player that allowed me to listen to music from my iPod. I paid a very fair price for it, and to this day it remains one of the best cars…

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CFPB must stop manipulating data to support its policy preferences

Americanbanker.com 
En

Part of the Consumer Financial Protection Bureau's mandate is to educate consumers by providing reliable information. With its credit card late fee "report" and the associated rulemaking, it has failed to live up to that responsibility.